Hi Everyone,

The issue with liver testing comes up every so often so I thought 
I'd address it here.  

When Gleevec was first tested in animals, there was clear evidence 
of both liver and kidney problems so it is standard procedure to 
check both the liver and kidneys routinely with Gleevec therapy in 
humans.

Unless your doctor is very well informed, he may not know the 
protocol for the various tests that should be done.  This is why 
these lists can be so important.  It has happenned several times 
before that patients have learned something from this list and gone 
to their doctors with the information and found out that their 
doctor wasn't following standard protocol.  

Unfortunatly we can't all have CML experts at the top CML centers 
treating all of us so there are valuable things to be learned from 
those who do go to these doctors and report back.  (Thank you Nancy 
C, your information is always invaluable).

As for frequency of testing, I guess different doctors will have 
different protocols.  I insist that I get everything checked with 
every blood test, which means I get the liver and kidney function 
tests along with my CBC and electrolytes roughly every 5-7 weeks.  I 
know of many doctors though who only do the more fancy tests every 2-
3 months.  In any case, they should be done at some regular interval.

Take care,
Tracey
dx Jan 2002
CCR July 2002
PCR neg Nov 2002








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