Hi Dave, I am in Montreal Quebec. I have heard of your doctor, he is a top doc in Atlantic Canada.
I am organizing a meeting for CML patients here in the Montreal are for January 28th (it's a Saturday) just in case you are interested in trying to join us, we will be about 50 CML patients. Let me know if you want more details. Cheers, Cheryl-Anne --- In CML@yahoogroups.com, "da06761" <[EMAIL PROTECTED]> wrote: > > Thank you for your reply! > > I am from Fredericton, New Brunswick. My Dr. is Dr. Cubon in > Halifax, NS. > > I did not ask that question, but I will. They did mention the 3 log > reducion, but I was under the impression that if I was put on 800mg > I would stay at that dosage until the 12mths was up. > > Dave > > > --- In CML@yahoogroups.com, "cher111376" <[EMAIL PROTECTED]> > wrote: > > > > Hi Dave, > > > > I am glad that you have been helped by these posts. > > > > I am aware of the trial you are speaking about as we have this > trial > > going on here in Montreal, Qc, Canada - where are you located. My > > Doctor here in Montreal is the P.I. for this trial. > > > > I know of a couple of patients who have participated in this trial > > and overall the higher dose has helped to improve the molecular > > response. Additionally, for the most part the increased dose did > not > > significantly increase side effects either. > > > > What isn't clear to me at the moment, and this is mostly because I > am > > PCRU and would therefore not qualify for this trial, so I didn't > ask > > this question before, is that once you achieve a 3 log reduct or > > better how long will you need to remain on the increased dose? > Have > > you asked this question? > > > > Thanks for posting, it is always interesting to hear from > people "out > > there". > > > > Cheers, > > Cheryl-Anne > > > > --- In CML@yahoogroups.com, "da06761" <[EMAIL PROTECTED]> wrote: > > > > > > Hi, > > > > > > My name is David, I have been a silent member for 4 years now > and > > to > > > start I want to thank everyone for their posts. They have helped > me > > > in a large way. > > > > > > My history is as follows: > > > > > > Name: Dave Blackier > > > dx age: 28 > > > dx: Dec 17th, 2001 > > > Gleevec: Since January 2002 > > > Current Dose: 400mg > > > > > > I started Gleevec at 600mg which caused my white blood cell > count > > to > > > drop. I was reduced to 300mg and gradually increase until I > reached > > > 600mg again. Once at 600mg I quickly achieved CCR followed by > MMR. > > I > > > was dropped to 400mg and have been there for 1.5 years now. > > > > > > > > > I have been asked to take part in a Novartis clinical trial > where > > > they will evaluating the effects of increasing the Gleevec > dosage > > to > > > 800mg on individuals that are currently having a molecular > response > > > at 400mg. The purpose of the trial is to understand whether > > > increasing Gleevec dosage has a positive effect on people who > have > > > had little luck at 400mg. I want to help, but where I have been > > > extremely sensitive to Gleevec past and I'm afraid of the side > > > effects of 800mg. I discussed this with my Doctor and he > approved > > of > > > my participation. Where my Doctor is the principal > investigator, I > > > would welcome everyone's feedback or opinions! > > > > > > Sorry for the length of the post. > > > > > > > > > Cheers! > > > Dave > > > > > > New! Sign up for local CML support group meetings in your local community at http://cml.meetup.com Apply for Commercial Real Estate loans online and submit your deal to dozens of hungry lenders in just minutes. Loan programs for all types of business and commercial real estate. Apply anytime at http://realestatezoo.com CML (Chronic Myelogenous Leukemia Support List) --------------------------------- Part Of CMLHope.Com An International Community Of CML Patients For more information: http://cmlhope.com Post Message: cml@yahoogroups.com Subscribe: [EMAIL PROTECTED] Unsubscribe: [EMAIL PROTECTED] Change To No Mail/Web: [EMAIL PROTECTED] Change To Digest: [EMAIL PROTECTED] Change To Email: [EMAIL PROTECTED] List Help: [EMAIL PROTECTED] CML Group Web Site http://groups.yahoo.com/group/CML Yahoo! Groups Links <*> To visit your group on the web, go to: http://groups.yahoo.com/group/CML/ <*> To unsubscribe from this group, send an email to: [EMAIL PROTECTED] <*> Your use of Yahoo! Groups is subject to: http://docs.yahoo.com/info/terms/
