Thanks, Trey.  That's helpful information for me, especially re the difference 
between suppression and compromise.  Appreciate the info.

chris in minn
  ----- Original Message ----- 
  From: Trey<mailto:[EMAIL PROTECTED]> 
  To: CMLHope<mailto:CMLHope@googlegroups.com> 
  Sent: Friday, November 17, 2006 8:35 AM
  Subject: [CMLHope] Re: No immune compromise if PCRU



  There is a difference between suppressing the immune system and
  compromising it, and the articles talk about suppression, not
  compromise.  If the WBCs are very low, as can occur in some CMLers on
  Gleevec, then it is suppressed and somewhat more susceptible to a virus
  or bacteria, but can still respond when a virus or bacteria invades the
  body by making new WBCs in sufficient quantity.  This is demonstrated
  when we get sick and have a CBC done, that CBC shows higher WBC levels.
   If an immune system is compromised, the body does not have the ability
  to make sufficient new WBCs when a virus or bacteria invades the body.
  If Gleevec truly compromised the immune system, we would all need to
  live in a bubble.  I think this distinction is important because we do
  not need to endlessly worry that Gleevec makes us weak and vulnerable
  to all sorts of dire consequences.  We can live a rather normal life,
  and not live in constant fear that we might have a compromised immune
  system that is unable to respond when needed.

  --Trey


  


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