Suzie I do not think you need to worry. Some variation is common, particularly in people with very low PCR numbers. There are certain labs in the world that are supposedly so good they think they can predict a relapse if the test result only doubles on 2 consecutive tests. Most CML experts think that is not routinely possible for most labs.
One suggestion that I have seen, of which I have yet to see any large amount of data, is to look for a minimum of a 10x jump with a trend to increasing % over several consecutive tests. This theory does not take into the context of someone such as your self with an extremely low BCR-ABL ratio. Your latest test result only basically doubled. For comparison, your 3/2006 to 7/2006 tripled but went back down on the next tests. I think this just reflects the variability of the testing. Wait and see what happens the next time. On Jun 24, 3:05 pm, Suzieq <[EMAIL PROTECTED]> wrote: > Well, after having the last one come in saying "none detected", this > one four months later came in with a huge jump......"positive: Major > Breakpoint 0.013%" > > I said a "huge" jump.....my husband didn't think it was so bad, but I > thought compared with past results, it was. This is how it's been > since 2/22/'05......0.006%; 6/14/05....0.008%; > 3/6/'06.....0.002%; 7/10/06.....0.007%; 10/18/06.....0.002%; > 2/7/07.....not detected; & now the 0.013%. > > My question is this....do I have anything to be concerned with.....or > is this just normal with Gleevec patients? I was hoping for it to > stay the same.....but guess not to be. > > Thanks, > Suzieq --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to CMLHope@googlegroups.com To unsubscribe from this group, send email to [EMAIL PROTECTED] For more options, visit this group at http://groups.google.com/group/CMLHope -~----------~----~----~----~------~----~------~--~---
