See recent posts this week about BM biopsy.

The recommendation is a marrow at diagnosis, 6 months and 12 months
after starting Gleevec.  Perhaps another one at 18 months depending on
how the person is responding.  Might skip this one if a Complete
Cytogenetic response (0/20 metaphases Ph+) was previously reached.
The recommendation thereafter is a marrow on a yearly basis.  These
recommendations might change in the future.

Ideally your husband should have a marrow test at 12 months from the
time he began Gleevec.  If that cannot be done, then it seems to me a
good idea to at least have a FISH and PCR test done on the blood.  The
recommendation is for a quantitative PCR test for BCR-ABL every 3
months (regardless of response to Gleevec).

On Mar 13, 9:54 pm, [EMAIL PROTECTED] wrote:
> My husband was diagnosed with CML in June and had his first BMB in  
> September.  We have since switched oncologists.  His  new oncologist says 
> that he does
> not need another BMB at the  present time because he is on Coumadin and
> doesn't want him to have it  because of the risk factor. (He is doing very 
> well on
> the Gleevec.)   Of course I don't want him to go through another painful BMB,
> but I also  feel that he is not getting the proper care because of the
> Coumadin.  Shouldn't a BMB be given every 6 months? I would appreciate any 
> feedback  
> and/or information.
>
> Blessings to you all,
> Lee
>
> **************It's Tax Time! Get tips, forms, and advice on AOL Money &
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