Hi Hoosha, You are not alone. I was also dx in 2004; everything was great until about 6 months ago. My platelets went up and never came back down to normal. I had been on 400 msg and it was upped to 600, which I have on for a while now. I had wondered if the 4 1/2 year mark on Gleevec was the time it quit working. If anyone in that year range has had Gleevec not working, please let us know and what you did. Blessings Jeanie<3 In a message dated 8/17/2008 11:44:50 A.M. Pacific Daylight Time, [EMAIL PROTECTED] writes:
Dear Friends: Hope all going well around everybody. I am 28 years old now. I was diagnosed CML in Nov 2004 with WBC = 230’000. I start 400mg of Gleevec and after 2 month I increase it to 600mg (until now). I was doing PCR test every 6 month and all of them was negative. So I was in Complete Molecular Response until January 2008 that my PCR was Positive. I done QPCR test at Feb 2008 which my BCR-ABL/ABL =0.182%. I redone my QPCR at Aug 2008 and my BCR-ABL/ABL = 0.49% I have a question. What should I do? Increasing my Gleevec to 800mg? Switching to Sprycel? stay at 600 mg and redone my QPCR test after 3 month? I didn’t have any side effect so I was in Gleevec without any interruption at these years. My WBC is 4500 now and my CBC is very good. Your opinions are so valuable for me Thank you in Advance Hoosha **************Looking for a car that's sporty, fun and fits in your budget? Read reviews on AOL Autos. (http://autos.aol.com/cars-Volkswagen-Jetta-2009/expert-review?ncid=aolaut00030000000007 ) --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to CMLHope@googlegroups.com To unsubscribe from this group, send email to [EMAIL PROTECTED] For more options, visit this group at http://groups.google.com/group/CMLHope -~----------~----~----~----~------~----~------~--~---