Dear Kevin,

Can you pls update more on Sprycel Study . My Son(11yrs) is on Gleevec 400
mg for last 2 yrs and now on 500mg .

regards

Anil Nagpal


On 8/19/08, [EMAIL PROTECTED] <[EMAIL PROTECTED]> wrote:
>
>
> Hi Jeanie and Hoosha,
>
> I was on 400 mg Gleevec for about 2 years and 800 mg for about one
> year. I never reached Complete Molecular Response on Gleevec. I
> enrolled on the Sprycel study and it was the best decision of my life.
> I am now in complete molecular remission.
>
> -Kevin Williams
>
> On Aug 18, 5:04 am, [EMAIL PROTECTED] wrote:
> > Hi Hoosha,
> > You are not alone.
> > I was also dx in 2004; everything was great until about 6  months ago.
> > My platelets went up and never came back down to  normal.
> > I had been on 400 msg and it was upped to 600, which I have on  for a
> while
> > now.
> > I had wondered if the 4 1/2 year mark on Gleevec was the time  it quit
> > working.
> > If anyone in that year range has had Gleevec not working,  please let us
> know
> > and what you did.
> > Blessings
> > Jeanie<3
> > In a message dated 8/17/2008 11:44:50 A.M. Pacific Daylight Time,
> >
> > [EMAIL PROTECTED] writes:
> >
> > Dear  Friends:
> >
> > Hope all going well around everybody.
> >
> > I am 28 years old  now. I was diagnosed CML in Nov 2004 with WBC =
> > 230'000. I start 400mg of  Gleevec and after 2 month I increase it to
> > 600mg (until now).  I was  doing PCR test every 6 month and all of them
> > was negative. So I was in  Complete Molecular Response until January
> > 2008 that my PCR was Positive. I  done QPCR test at Feb 2008 which my
> > BCR-ABL/ABL =0.182%. I redone my QPCR  at Aug 2008 and my
> > BCR-ABL/ABL = 0.49%
> >
> > I have a question. What  should I do? Increasing my Gleevec to 800mg?
> > Switching to Sprycel? stay at  600 mg and redone my QPCR test after 3
> > month?
> >
> > I didn't have any side  effect so I was in Gleevec without any
> > interruption at these years.
> > My  WBC is 4500 now and my CBC is very good.
> >
> > Your opinions are so  valuable for me
> > Thank you in Advance
> > Hoosha
> >
> > **************Looking for a car that's sporty, fun and fits in your
> budget?
> > Read reviews on AOL Autos.
> > (http://autos.aol.com/cars-Volkswagen-Jetta-2009/expert-review?ncid=ao..
> .)
> >
>


-- 
Regards

Anil Nagpal

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