Rien, It would be best to wait for the next PCR result. It could be undetectable again. But if it continues to rise, the mutation analysis would be useful. But approximately 30% of Gleevec failures are due to other reasons, so it is not always the complete answer. A rising PCR would suggest the need to switch medications. Increasing from 600mg to 800mg would not likely be the right answer. You would benefit more from switching drugs.
Regarding the colon cleansing, it would be best to irrigate within a couple hours after taking Gleevec. The previous dosage would be mostly eliminated at that point, and the new dosage would not have reached the colon by then. You should avoid irrigating from 3 hours to 18 hours after taking Gleevec. --~--~---------~--~----~------------~-------~--~----~ [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to CMLHope@googlegroups.com To unsubscribe from this group, send email to cmlhope-unsubscr...@googlegroups.com For more options, visit this group at http://groups.google.com/group/CMLHope -~----------~----~----~----~------~----~------~--~---