Hi Choi, Pleural Effusions are quite common to people that are using Sprycel sometimes even on low doses. Since he also has the E55G mutation he or you may want to get in touch with Dr. Brian Druker and Dr. Moshie Talpaz. Both of these doctors are the CML experts Dr. Druker was the one that made STI-571 later to become Gleevec. Mailing Address
Oregon Health & Science University 3181 S.W. Sam Jackson Park Road Telephone NumberGeneral information 503 494-8311 Portland, OR 97239. Or Dr. Moshie Talpaz. U of M Internal Medicine Hematology/Oncology <http://maps.google.com/maps?q=1500%20E%20Medical%20Center%20Dr%20%205911> Cancer Center Floor B1 Reception B 1500 E Medical Center Dr SPC 5911 Ann Arbor MI 48109 Phone: 734-647-8901 Fax: 734-647-866 Good luck 18's Symbol for life Marty On Tue, Jun 9, 2015 at 6:47 AM, Choi <saehyun...@naver.com> wrote: > Hi, this is Choi from South Korea. One of my CML friends had some problems > and I just wonder who had a similar experience. > > He was diagnosed with CML chronic phase on july 2012 and started Gleevec > 400mg for 16 months and switched to Sprycel due to E355G mutation. > At that time his PCR was 1.89. He started Sprycel and E355G mutaiton was > disappered. He was on Sprycel for 12 months. > He developed pleural effusions after 12 months of Sprycel at that time his > dose was 100mg. His doctor stopped Sprycel for 2 weeks and restarted > Sprycel 80mg for 3 months. > Once again he developed pleural effusions so he was off Sprycel for 4 > weeks and restarted Sprycel 60mg until now and still had minor pleural > effusions. > PCR count was 0.37, 0.47, 0.45 and never drop to under 0.1% so his doctor > was considering to switch to other drugs but hesitated to switch because of > he had E355G mutation. > Is there any one who had a similar experience? > > Choi. > > -- > -- > [CMLHope] > A support group of http://cmlhope.com > ------------------------------------------------- > > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To post to this group, send email to CMLHope@googlegroups.com > To unsubscribe from this group, send email to > cmlhope-unsubscr...@googlegroups.com > For more options, visit this group at > http://groups.google.com/group/CMLHope > --- > You received this message because you are subscribed to the Google Groups > "CMLHope" group. > To unsubscribe from this group and stop receiving emails from it, send an > email to cmlhope+unsubscr...@googlegroups.com. > For more options, visit https://groups.google.com/d/optout. > -- -- [CMLHope] A support group of http://cmlhope.com ------------------------------------------------- You received this message because you are subscribed to the Google Groups "CMLHope" group. To post to this group, send email to CMLHope@googlegroups.com To unsubscribe from this group, send email to cmlhope-unsubscr...@googlegroups.com For more options, visit this group at http://groups.google.com/group/CMLHope --- You received this message because you are subscribed to the Google Groups "CMLHope" group. To unsubscribe from this group and stop receiving emails from it, send an email to cmlhope+unsubscr...@googlegroups.com. For more options, visit https://groups.google.com/d/optout.
