Thanks John. I am surprised that I have not seen anything about that drug
before. Been researching in this CML department since 2008.
Joyce in IL
On Jun 9, 2015, at 10:32 PM, John Barrons wrote:
> Hi Joyce: if you go to drugs.com and type in name omacetaxine is well
> explained. It requires an injection twice a day, which I did. I was on it
> about two years. I have been 100% Phillies until I started ponatinib and this
> drug reduced my phone Phillies to about 50%. I am very sensitive to ponatinib
> as it is a strong medication. There are some issues with side effects with
> the heart. Right now I am off the drug for a three week period and will
> probably go on one pill a week when get a cbc. My counts are WB 3.5,
> platelets 17 and red blood 116. I am sorry your husband is involved with
> this but at least the drugs are pretty good. I have had cml for 15 and one
> half years.
> Cheers John B
>
> Sent from my iPad
>
> On Jun 9, 2015, at 11:00 PM, Joyce Mesnarich <joy...@htc.net> wrote:
>
>> John,
>> When you were on sprycel did you get to PCRU? My husband was on sprycel for
>> 3 years and then, just as you, had to go off because of pleural effusion.
>> He was undetectable for 2 years and lost his PCRU in 2 months. He is now on
>> bosulif.....first 100 mg which was not working.....then on 200 mg which he
>> will find out in July if it is doing anything good.
>> I am not familiar with omacetaxine. Can you enlighten us on what it is and
>> what it is for?
>> Wish you well on ponatinib.
>> Joyce in IL
>>
>>
>> On Jun 9, 2015, at 6:31 AM, John Barrons wrote:
>>
>>> Hi Choi I was on sprycel and to go off it because of pleural effusion. I
>>> then went on omacetaxine for a couple of years and finally am on ponatinib.
>>> I only take normally one pill a week it is a strong drug so I am off it for
>>> three weeks. John B
>>>
>>>
>>>
>>>
>>>
>>>
>>>
>>>
>>>
>>>
>>> Sent from my iPad
>>>
>>> On Jun 9, 2015, at 6:47 AM, Choi <saehyun...@naver.com> wrote:
>>>
>>>> Hi, this is Choi from South Korea. One of my CML friends had some problems
>>>> and I just wonder who had a similar experience.
>>>>
>>>> He was diagnosed with CML chronic phase on july 2012 and started Gleevec
>>>> 400mg for 16 months and switched to Sprycel due to E355G mutation.
>>>> At that time his PCR was 1.89. He started Sprycel and E355G mutaiton was
>>>> disappered. He was on Sprycel for 12 months.
>>>> He developed pleural effusions after 12 months of Sprycel at that time his
>>>> dose was 100mg. His doctor stopped Sprycel for 2 weeks and restarted
>>>> Sprycel 80mg for 3 months.
>>>> Once again he developed pleural effusions so he was off Sprycel for 4
>>>> weeks and restarted Sprycel 60mg until now and still had minor pleural
>>>> effusions.
>>>> PCR count was 0.37, 0.47, 0.45 and never drop to under 0.1% so his doctor
>>>> was considering to switch to other drugs but hesitated to switch because
>>>> of he had E355G mutation.
>>>> Is there any one who had a similar experience?
>>>>
>>>> Choi.
>>>>
>>>> --
>>>> --
>>>> [CMLHope]
>>>> A support group of http://cmlhope.com
>>>> -------------------------------------------------
>>>>
>>>> You received this message because you are subscribed to the Google Groups
>>>> "CMLHope" group.
>>>> To post to this group, send email to CMLHope@googlegroups.com
>>>> To unsubscribe from this group, send email to
>>>> cmlhope-unsubscr...@googlegroups.com
>>>> For more options, visit this group at
>>>> http://groups.google.com/group/CMLHope
>>>> ---
>>>> You received this message because you are subscribed to the Google Groups
>>>> "CMLHope" group.
>>>> To unsubscribe from this group and stop receiving emails from it, send an
>>>> email to cmlhope+unsubscr...@googlegroups.com.
>>>> For more options, visit https://groups.google.com/d/optout.
>>>
>>>
>>> --
>>> --
>>> [CMLHope]
>>> A support group of http://cmlhope.com
>>> -------------------------------------------------
>>>
>>> You received this message because you are subscribed to the Google Groups
>>> "CMLHope" group.
>>> To post to this group, send email to CMLHope@googlegroups.com
>>> To unsubscribe from this group, send email to
>>> cmlhope-unsubscr...@googlegroups.com
>>> For more options, visit this group at http://groups.google.com/group/CMLHope
>>> ---
>>> You received this message because you are subscribed to the Google Groups
>>> "CMLHope" group.
>>> To unsubscribe from this group and stop receiving emails from it, send an
>>> email to cmlhope+unsubscr...@googlegroups.com.
>>> For more options, visit https://groups.google.com/d/optout.
>>
>>
>> --
>> --
>> [CMLHope]
>> A support group of http://cmlhope.com
>> -------------------------------------------------
>>
>> You received this message because you are subscribed to the Google Groups
>> "CMLHope" group.
>> To post to this group, send email to CMLHope@googlegroups.com
>> To unsubscribe from this group, send email to
>> cmlhope-unsubscr...@googlegroups.com
>> For more options, visit this group at http://groups.google.com/group/CMLHope
>> ---
>> You received this message because you are subscribed to the Google Groups
>> "CMLHope" group.
>> To unsubscribe from this group and stop receiving emails from it, send an
>> email to cmlhope+unsubscr...@googlegroups.com.
>> For more options, visit https://groups.google.com/d/optout.
>
>
> --
> --
> [CMLHope]
> A support group of http://cmlhope.com
> -------------------------------------------------
>
> You received this message because you are subscribed to the Google Groups
> "CMLHope" group.
> To post to this group, send email to CMLHope@googlegroups.com
> To unsubscribe from this group, send email to
> cmlhope-unsubscr...@googlegroups.com
> For more options, visit this group at http://groups.google.com/group/CMLHope
> ---
> You received this message because you are subscribed to the Google Groups
> "CMLHope" group.
> To unsubscribe from this group and stop receiving emails from it, send an
> email to cmlhope+unsubscr...@googlegroups.com.
> For more options, visit https://groups.google.com/d/optout.
--
--
[CMLHope]
A support group of http://cmlhope.com
-------------------------------------------------
You received this message because you are subscribed to the Google Groups
"CMLHope" group.
To post to this group, send email to CMLHope@googlegroups.com
To unsubscribe from this group, send email to
cmlhope-unsubscr...@googlegroups.com
For more options, visit this group at http://groups.google.com/group/CMLHope
---
You received this message because you are subscribed to the Google Groups
"CMLHope" group.
To unsubscribe from this group and stop receiving emails from it, send an email
to cmlhope+unsubscr...@googlegroups.com.
For more options, visit https://groups.google.com/d/optout.
