-Caveat Lector-

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Is Nicotine Good For The Heart?
August 03, 2001
What is probably the number one drug problem that we have? Well, of
course, you know the answer is cigarettes and nicotine. Well, here comes a
story that will probably shock you. Researchers at Stanford University have
just published the results of a study that shows that nicotine may actually be
good for the heart.
As a medical student, our pharmacology class began with the study of
nicotine because it is a drug with straightforward effects on the body. It’s a
good introduction to drugs and their effects.
Here is what we know about nicotine. When we give people nicotine patches,
after they’ve been smoking for years and are trying to quit, their hearts get
better. Now, we always thought that was because when you smoke, you’re
taking in carbon monoxide and other things that are bad for the heart. So, if
you eliminate the gases the heart would improve. We still considered
nicotine bad for the heart. We never correlated the heart improvement with
nicotine.
Well, now the research has become more refined, and researchers have
found that nicotine has quite an effect on the formation of new blood vessels
following a heart attack or stroke. This is just the effect you want in a heart
drug. Remember that all this work is being conducted in the lab and not in
humans, so things may change a bit when clinical research begins in human
subjects.
Still, this finding doesn’t surprise me, because there are thousands of
byproducts that can affect your health. We don’t even know what causes
lung cancer. Theories range from radiation that comes from the fertilizer used
to grow tobacco, to the aromatic hydrocarbons that are produced by burning
any vegetable matter. The burning vegetable matter theory is directly
contradicted by evidence in marijuana use. Marijuana users don’t get lung
cancer, and we don’t know why that is either. So we’ve got to keep an open
mind, and listen.
We also think that nicotine decreases your risk for colitis, Crone’s disease,
Parkinson’s disease, and the list goes on.
Source: Nature Medicine, Vol 7, No. 7, pp 833-839, July 2001

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