> Allowing ray to automatically set -minimumCoverage and -peakCoverage the 
> estimated coverage and genome length is completely wrong


Why is that so ?




> I'm interested in knowing how ray uses such parameters: it simply deletes all 
> nodes in the k-mer graph that are composed by kmers that appear more than 
> peakCoverage or it does some more sophisticated?

In short, it does some more sophisticated things.


Go read our publications to learn how Ray works.

http://denovoassembler.sourceforge.net/publications.html

You can also read files from the directory Documentation/

https://github.com/sebhtml/ray/tree/master/Documentation



> Moreover, how -repeatCoverage affects the assembler performances and the 
> final result?

In my opinion, these parameters should remained untouched. Ray does a great job 
at finding these values if your data has redundant k-mers.




> ________________________________________
> De : Francesco Vezzi [[email protected]]
> Date d'envoi : 31 août 2011 04:40
> À : [email protected]
> Objet : [Denovoassembler-users] Peak coverage option
> 
> Dear Ray users and developers,
> I'm using Ray in order to assemble an highly repetitive plant genome using 
> Illumina and 454 reads. It is well known that the genome is composed of long 
> stretches of microsatellites.
> Allowing ray to automatically set -minimumCoverage and -peakCoverage the 
> estimated coverage and genome length is completely wrong. I'm interested in 
> knowing how ray uses such parameters: it simply deletes all nodes in the 
> k-mer graph that are composed by kmers that appear more than peakCoverage or 
> it does some more sophisticated?
> 
> Moreover, how -repeatCoverage affects the assembler performances and the 
> final result?
> 
> Thanks
> Francesco
> 
> --
> 
> Francesco Vezzi, PhD Student
> Tel: +39 3805151541
> Department of Mathematics and Computer Science,
> University of Udine, Udine, Italy
> &
> Applied Genomics Institute (IGA), Udine, Italy
> http://www.appliedgenomics.org
> 
> 
> 
> 
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