== Quote from Nick Sabalausky (a...@a.a)'s article But, yes, obviously there are going to be fringe-case > exceptions even with this, such as researchers writing custom DNA-processing > code that's only ever going to run on their super-duper-cluster.)
I'm one of these researchers, and it would make my life a heck of a lot easier if I could fit the entire human genome in my address space. I don't do that much sequence analysis, or lack of 64-bit would be a deal-breaker for D. I mostly do microarray analysis, which usually fits much better in 32-bit address space, unless I start doing things like pairwise analysis among probes (some machine learning techniques require this). However, once in a while when my research does take a turn into genome sequence land, the 2-gig address space limit feels like a HUGE artificial limitation. The alternative is to switch to nematode genomics, as their genome could have fit into my old Pentium II's RAM.