Hello Daniel,
Although, in that case, it probably wouldn't hurt anything (aside from memory usage)
if that's a problem, you have bigger problems. :)
to simply statically link the runtime and standard library in; if the host app is C/C++, then the plugins probably won't be able to stomp all over each other.
Much of the time you should be safe. But if the plugins are allowed to interact (pass data around) and you have two written in D you would need to take care.