You could do this in Django. Creating and editing the XML in JavaScript sounds 
like masochism. Why not just use Python? I agree with Brice's comment -- can 
you make things easier on yourself and use JSON instead of XML?

Also, if you can use JSON, you might have a natural fit using MongoDB, which 
has a Python library (pymongo). Or you could save serialized JSON in a Postgres 
or MySQL database using Django and simplejson (which also is included in 
Django). Maybe even a combination where the "blobs" (as you call them) are 
stored in MongoDB (which allows you all kinds of cool functionality) and the 
other data can be in the database that Django handles.

Shawn


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