Just specify an argument for --settings when you launch the server for each instance.
example (development): ./manage.py runserver --settings=myproject.myapp.special_settings Sawn -- You received this message because you are subscribed to the Google Groups "Django users" group. To post to this group, send email to django-us...@googlegroups.com. To unsubscribe from this group, send email to django-users+unsubscr...@googlegroups.com. For more options, visit this group at http://groups.google.com/group/django-users?hl=en.