Dear Ibu Saraswati,
Saya turut prihatin atas anak ibu yang menderita ITP (Idiopathic
Thrombocytopenic Purpura), suatu keadaan penurunan kadar trombosit yang
disertai gejala perdarahan (ringan-berat), misalnya bintik2 merah di kulit
atau mimisan, yang sebabnya tidak diketahui (biasanya autoimun = imun tubuh
sendiri menghancurkan trombosit dalam tubuh sendiri), biasa terjadi beberapa
minggu setelah infeksi virus (flu?), atau obat-obatan, atau penyakit
autoimun lain yg tidak terdeteksi, atau bisa juga timbul 'begitu' saja.
Lameson adalah sejenis steroid, yang disini berfungsi untuk menekan sistem
immun pada anak, sehingga mengurangi reaksi autoimun tersebut, dan
diharapkan pengrusakan trobosit oleh tubuh bisa ditekan, sehingga produksi
trombosit oleh tubuh bisa mengejar penghancuran oleh sistem imun.
Jadi saran saya, terus kontrol ke dokter anaknya, dan hindarkan anak dari
aktivitas yg beresiko menimbulkan trauma (misal lari-larian) apabila kadar
trobosit masih relatif rendah ( <75.000).
Jangan menghentikan penggunaan Lameson secara mendadak, harus sesuai saran
dokter karena nanti dosis akan diturunkan secara bertahap (tapering off).
ITP *biasanya* akan sembuh sendiri dalam waktu maximum 6 bulan.
Berikut informasi lebih lengkap mengenai itp
ITP stands for Immune (also referred to as idiopathic) Thrombocytopenic (a
decreased platelet number) Purpura (purplish areas of skin and mucous
membranes).
You may also hear the term "Idiopathic" Thrombocytopenic Purpura which
means the cause of the low platelets is unknown.
ITP occurs when a person makes antiplatelet antibodies which attach to
his/her own platelets. The antibodies cause the immune system to destroy the
platelets. This results in a decrease in the platelet count.
Platelets are the blood cells that help form clots to stop bleeding.
A blood test is done to count the number of platelets you /your child
has.
A normal platelet count is higher than 150,000/mm3.
Hematologists generally agree that platelet counts:
higher than 100,000/mm3 are always safe,
higher than 30,000/mm3 are nearly always safe, and
lower than 10,000/mm3 may be associated with an increased risk of
bleeding.
The cause of ITP is not known.
ITP has been associated with:
recent viral infection,
some medications,
immune disorders (including Lupus), and
infections.
There is nothing you did to cause ITP.
ITP is not contagious.
There is no cure for ITP. Fortunately, most childhood cases resolve on
their own.
The main reason to treat ITP is to keep you/your child's platelet count in a
safe range so that the risk of bleeding is minimized.
Platelet counts lower than 10,000 may increase the risk of bleeding.
Therapy temporarily raises the platelet count to minimize the bleeding
risk.
The treatment for ITP may include:
observation (monitoring platelet counts),
stopping medications that are thought to cause ITP, and
treating infections.
Other treatments such as steroids, Winrho, IVIG, and/or
6-mercaptopurine infusions may be considered. These medications help to trick
the body's response so that it does not destroy the platelets.
In some instances a splenectomy (removal of the spleen) may be
recommended.
Platelet counts may go up and down for many months.
Childhood ITP usually resolves itself within 6 months.
Some patients do not resolve within this period of time and continue
with Chronic ITP.
Some patients may also require several courses of treatment before the
ITP resolves at a later time.
http://www.itpkids.org/content/about_itp.html
Demikian sedikit masukan dari saya, semoga bermanfaat.
Salam,
Peter, dr.
2009/3/18 Ummu Farhan <[email protected]>
> Maaf bu,
> ITP itu penyakit apa ya?gimana gejalanya?kalau ibu saya batuk kering
> biasanya makan lameson tab.untuk mengurangi rasa gatal di tenggorokan
> i
> Sent from my BlackBerry®
> powered by Sinyal Kuat INDOSAT
>
> -----Original Message-----
> From: "Krisna" <[email protected]>
>
> Date: Tue, 17 Mar 2009 21:58:58
> To: <[email protected]>
> Subject: [Dokter Umum] Apakah Lameson Tab 16 Mg cocok untuk therapi ITP
> -urgent please
>
>
> Seminggu yang lalu putri saya yang berusia 4 tahun positif dinyatakan
> menderita ITP oleh Dokter Anak, di salah satu Rumah Sakit Di Cikarang.
>
> Pada waktu pengecekan trombosit darah cuma 7000, dan dokter menyarankan
> agar diopname. Setelah tiga hari perawatan dengan transfusi trombocyte
> extract, akhirnya trombocytenya meningkat menjadi 158000.
> Anak saya diperbolehkan pulang dengan catatan harus control seminggu
> sekali, dan dokter memberikan Lameson Tab 16 Mg untuk memacu pembentukan
> trombocyte katanya.
>
> Pada minggu berikutnya saya control kembali kerumah sakit tersebut dan
> ternyata trombocytenya turun kembali menjadi 51000. Kali ini dokternya
> kembali meminta agar konsumsi Lamesonnya diteruskan, dan menyuruh anak saya
> banyak2 istirahat.
>
> Saya mencoba mencari referensi obat Lameson tersebut tapi tidak
> menemukannya , mohon informasi dari rekan rekan milis yang mengetahui .
> Kondisi anak saya saat ini cukup mengkuatirkan.
>
>
> Atas perhatian dan bantuannya saya ucapkan terima kasih
>
>
>
> Ibu Saraswati
>
>
>
>
> [Non-text portions of this message have been removed]
>
>
>
> ------------------------------------
>
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>
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