Terima kasih Dr Peter, atas informasinya. Apakah ada effek samping dari obat ini ? atas penjelasannya saya ucapkan terima kasih
Ibu Saraswati -- In [email protected], Peter K <physi...@...> wrote: > > Dear Ibu Saraswati, > > Saya turut prihatin atas anak ibu yang menderita ITP (Idiopathic > Thrombocytopenic Purpura), suatu keadaan penurunan kadar trombosit yang > disertai gejala perdarahan (ringan-berat), misalnya bintik2 merah di kulit > atau mimisan, yang sebabnya tidak diketahui (biasanya autoimun = imun tubuh > sendiri menghancurkan trombosit dalam tubuh sendiri), biasa terjadi beberapa > minggu setelah infeksi virus (flu?), atau obat-obatan, atau penyakit > autoimun lain yg tidak terdeteksi, atau bisa juga timbul 'begitu' saja. > > Lameson adalah sejenis steroid, yang disini berfungsi untuk menekan sistem > immun pada anak, sehingga mengurangi reaksi autoimun tersebut, dan > diharapkan pengrusakan trobosit oleh tubuh bisa ditekan, sehingga produksi > trombosit oleh tubuh bisa mengejar penghancuran oleh sistem imun. > > Jadi saran saya, terus kontrol ke dokter anaknya, dan hindarkan anak dari > aktivitas yg beresiko menimbulkan trauma (misal lari-larian) apabila kadar > trobosit masih relatif rendah ( <75.000). > Jangan menghentikan penggunaan Lameson secara mendadak, harus sesuai saran > dokter karena nanti dosis akan diturunkan secara bertahap (tapering off). > > ITP *biasanya* akan sembuh sendiri dalam waktu maximum 6 bulan. > > Berikut informasi lebih lengkap mengenai itp > > ITP stands for Immune (also referred to as idiopathic) Thrombocytopenic (a > decreased platelet number) Purpura (purplish areas of skin and mucous > membranes). > > You may also hear the term "Idiopathic" Thrombocytopenic Purpura which > means the cause of the low platelets is unknown. > > ITP occurs when a person makes antiplatelet antibodies which attach to > his/her own platelets. The antibodies cause the immune system to destroy the > platelets. This results in a decrease in the platelet count. > > Platelets are the blood cells that help form clots to stop bleeding. > > A blood test is done to count the number of platelets you /your child > has. > > A normal platelet count is higher than 150,000/mm3. > > Hematologists generally agree that platelet counts: > > higher than 100,000/mm3 are always safe, > > higher than 30,000/mm3 are nearly always safe, and > > lower than 10,000/mm3 may be associated with an increased risk of > bleeding. > > > The cause of ITP is not known. > > ITP has been associated with: > > recent viral infection, > > some medications, > > immune disorders (including Lupus), and > > infections. > > There is nothing you did to cause ITP. > > ITP is not contagious. > > There is no cure for ITP. Fortunately, most childhood cases resolve on > their own. > > > The main reason to treat ITP is to keep you/your child's platelet count in a > safe range so that the risk of bleeding is minimized. > > Platelet counts lower than 10,000 may increase the risk of bleeding. > > Therapy temporarily raises the platelet count to minimize the bleeding > risk. > > > The treatment for ITP may include: > > observation (monitoring platelet counts), > > stopping medications that are thought to cause ITP, and > > treating infections. > > Other treatments such as steroids, Winrho, IVIG, and/or > 6-mercaptopurine infusions may be considered. These medications help to trick > the body's response so that it does not destroy the platelets. > > In some instances a splenectomy (removal of the spleen) may be > recommended. > > Platelet counts may go up and down for many months. > > Childhood ITP usually resolves itself within 6 months. > > Some patients do not resolve within this period of time and continue > with Chronic ITP. > > Some patients may also require several courses of treatment before the > ITP resolves at a later time. > > http://www.itpkids.org/content/about_itp.html > > Demikian sedikit masukan dari saya, semoga bermanfaat. > > Salam, > Peter, dr. > >
