Located Eric's message and can confirm the same for mu4e (no query about setting/evaluating anything upon opening the message).
cm Eric S Fraga writes: > On Wednesday, 25 Nov 2020 at 15:38, Jean Louis wrote: >> I have not configured anything. In fact I have opened the email and I >> was surprised that I am getting those dialogues to execute local >> variables. > > Very strange. It was my email that instigated this part of the > thread. I can view my email and I do not get asked to set any locate > variables or, in this case, evaluate the elisp expression. Out of > curiosity, what mail reader did you use that actually interprets file > local variables? Gnus article view does not.