I will chime in with a big thumbs up vote for Ironport as well. We had to switch to them in a hurry at the end of last year and it's been great. We use the encryption piece as well, which has worked well. There is a built-in SSN trigger plus you can set up your own. We haven't tuned the anti-spam since the first day. We had installation support, about half a day, but our other site got theirs running by looking at our config and using the support site. Their support KB has answered many questions for me as well. Reputation filtering knocks off about 98% before the connection can even be completed. I don't know alot about how its price compares to others but we have been very happy with it so far.
---------------------------- Mary Anthes Network Engineer SCL Health System Lenexa, KS 66219 ~ Ninja Email Security with Cloudmark Spam Engine Gets Image Spam ~ ~ http://www.sunbeltsoftware.com/Ninja ~