Have you tried restarting the routing engine?  Maybe the routing tables are 
hosed.

From: Al Rose [mailto:arose...@gmail.com]
Sent: Monday, June 06, 2011 1:00 PM
To: MS-Exchange Admin Issues
Subject: Re: URGENT: You do not have permission to send to this recipient 
smtp;550 5.7.1 Unable to relay for

These errors include internal emails indeed.

I have checked the recipient policies and nothing changed, i can still see the 
domain name listed.

Thank you
On Mon, Jun 6, 2011 at 7:46 PM, Peter Johnson 
<peter.john...@peterstow.com<mailto:peter.john...@peterstow.com>> wrote:
Exchange 2003? Do these errors include internal e-mails? Have you changed the 
recipient policy and perhaps inadvertently removed your internal domain? I've 
had this happen to a customer before in a past life :) Is the exchange system 
perhaps no longer authoritative for the internal domain name?

Regards
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From: Al Rose [mailto:arose...@gmail.com<mailto:arose...@gmail.com>]
Sent: 06 June 2011 07:07 PM

To: MS-Exchange Admin Issues
Subject: Re: URGENT: You do not have permission to send to this recipient 
smtp;550 5.7.1 Unable to relay for

We are indeed using a smart host, i contacted the admin for this one and they 
said everything is OK...


I reverted back the relay settings to what they were.

Relay Restrictions:
Only the list below
(empty list)

Box checked Allow all computers which succesfully authenticate to relay

Still NDRs

To see i have disabled Antigen SMTP scan but no luck
On Mon, Jun 6, 2011 at 6:11 PM, Simon Butler 
<si...@sembee.co.uk<mailto:si...@sembee.co.uk>> wrote:
You don't have to touch relay settings at all if the client machines are all 
Outlook MAPI clients (instead of POP3/IMAP/SMTP).
What server is generating the NDR? Are you using a smart host? If so, have you 
checked it is still able to relay email for your server?

Simon.


--
Simon Butler
MVP: Exchange, MCSE
Sembee Ltd.

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Need cheap certificates for Exchange, compatible with the iPhone?
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Exchange Resources: http://exbpa.com/



From: Al Rose [mailto:arose...@gmail.com<mailto:arose...@gmail.com>]
Sent: 06 June 2011 15:34
To: MS-Exchange Admin Issues
Subject: URGENT: You do not have permission to send to this recipient smtp;550 
5.7.1 Unable to relay for

Hi,

Exchange 2003 SP2, clients Outlook 2003

All of a sudden all emails in our ORG generate NDRs: You do not have permission 
to send to this recipient smtp;550 5.7.1 Unable to relay for 
u...@acme.com<mailto:u...@acme.com>

Havent touched config in Exchange, but tried to restart SMTP service on all 
front end servers and do the following fix:


select your virtual smtp server and right click then options. if you have 2 
virtual servers choose the one that connects to the outside.

 go to access tab and click on relay.

choose "only that list"

make sure you untick the autorize relay to autenticated computers check box.

click on the users button and check both check boxes for authenticated users.



Any ideas?

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