Amani...
I understand your reasoning and have no rebuttal as I had not really
considered this... As it makes sense to address anemia BEFORE it
becomes life threatening perhaps it would make sense to start Epogen( or
similar) well before all the progenitors are wiped out.... My young boy
Yogi ( who is riddled with FeLV related problems... ) is mildly anemic
and I was , in fact, considering starting the drug before his numbers
drop too substantially...... Very aggravating that my current Vet
appeared willing, initially, to write me a script for Winstrol but took
back the offer after she spoke to the clinics director... Can't afford
to keep changing Vets
want someone with at least a " little " investment in my guy and who has
a sense of his history...
On Mon, Sep 19, 2016 at 01:00 PM, felvtalk-requ...@felineleukemia.org
wrote:
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Today's Topics:
1. FW: Epogen and other RBC enhancing drugs.... (Amani Oakley)
----------------------------------------------------------------------
Message: 1
Date: Mon, 19 Sep 2016 16:19:56 +0000
From: Amani Oakley To: "felvtalk@felineleukemia.org" Subject:
[Felvtalk] FW: Epogen and other RBC enhancing drugs....
Message-ID:
Content-Type: text/plain; charset="utf-8"
It's not the same, Robert, and I am not sure it would work. The Epogen
acts on the kidneys to secrete erythropoietin, which is a hormone that
tells the bone marrow to produce more red cells.
The problem, in my opinion, is that the FeLV infiltrates the red cell
progenitor cells in the bone marrow and either kills them or takes
them over so that they make viruses, not red cells. My hypothesis is
that when the red cell production stops, it is because all the
progenitor cells have been destroyed or taken over the by virus. Thus,
giving Epogen probably won't be helpful, because the cells which
normally respond to erythropoietin by creating more red cells, can no
longer do so because the progenitor cells are damaged or dead and can
no longer produce red cells.
Winstrol is known to be good for osteoporosis. My hypothesis is that
it strengthens the bone marrow by encouraging the growth of new cells
in the bone marrow. That would explain how red cell production gets
started back up again with the use of Winstrol.
With the Epogen, it is causing more erythropoietin to be produced to
"tell" the progenitor cells to produce red cells, but the progenitor
cells are either dead or damaged by the virus and can no longer
respond appropriately to the detection of higher levels of
erythropoietin. Epogen might work if you start it before the bone
marrow is really devastated - ie - before you get the big drop in red
cells and haematocrit.
Fair warning though: this is all my hypothesis, based on my own
observations, research and experience.
Amani
-----Original Message-----
From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf
Of ROBERT CHAPEL
Sent: September-18-16 5:22 AM
To: felvtalk@felineleukemia.org
Cc: felvtalk@felineleukemia.org
Subject: Re: [Felvtalk] Epogen and other RBC enhancing drugs....
Wondering if anyone in the group has any experience with Epogen or
Procrit ( and other such RBC enhancing drugs typically used with
Kidney Failure patients)....?? It's appears to be quite a bit cheaper
when used for veterinary purposes than human....?? As the go to drug
for anemia in Kidney patients it would stand to reason that it "
should" work for Feline anemia......??? There will not be the same
resistance to using this as we encounter attempting to procure
Winstrol......
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