Yes, Robert, I would think that it makes sense to try to get ahead of the problem. Just purely on a logical basis, while the bone marrow is still able to produce red cells, get him started on the Epogen and see if that helps. I also would again recommend Doxycycline in the hopes that it would act to keep the viral load down.
Amani -----Original Message----- From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf Of ROBERT CHAPEL Sent: September-20-16 6:53 AM To: felvtalk@felineleukemia.org Cc: felvtalk@felineleukemia.org Subject: Re: [Felvtalk] Epogen and similiars Amani... I understand your reasoning and have no rebuttal as I had not really considered this... As it makes sense to address anemia BEFORE it becomes life threatening perhaps it would make sense to start Epogen( or similar) well before all the progenitors are wiped out.... My young boy Yogi ( who is riddled with FeLV related problems... ) is mildly anemic and I was , in fact, considering starting the drug before his numbers drop too substantially...... Very aggravating that my current Vet appeared willing, initially, to write me a script for Winstrol but took back the offer after she spoke to the clinics director... Can't afford to keep changing Vets want someone with at least a " little " investment in my guy and who has a sense of his history... On Mon, Sep 19, 2016 at 01:00 PM, felvtalk-requ...@felineleukemia.org wrote: > Send Felvtalk mailing list submissions to > felvtalk@felineleukemia.org > > To subscribe or unsubscribe via the World Wide Web, visit > > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > or, via email, send a message with subject or body 'help' to > felvtalk-requ...@felineleukemia.org > > You can reach the person managing the list at > felvtalk-ow...@felineleukemia.org > > When replying, please edit your Subject line so it is more specific > than "Re: Contents of Felvtalk digest..." > > > Today's Topics: > > 1. FW: Epogen and other RBC enhancing drugs.... (Amani Oakley) > > > ---------------------------------------------------------------------- > > Message: 1 > Date: Mon, 19 Sep 2016 16:19:56 +0000 > From: Amani Oakley To: "felvtalk@felineleukemia.org" Subject: > [Felvtalk] FW: Epogen and other RBC enhancing drugs.... > Message-ID: > > Content-Type: text/plain; charset="utf-8" > > > It's not the same, Robert, and I am not sure it would work. The Epogen > acts on the kidneys to secrete erythropoietin, which is a hormone that > tells the bone marrow to produce more red cells. > > The problem, in my opinion, is that the FeLV infiltrates the red cell > progenitor cells in the bone marrow and either kills them or takes > them over so that they make viruses, not red cells. My hypothesis is > that when the red cell production stops, it is because all the > progenitor cells have been destroyed or taken over the by virus. Thus, > giving Epogen probably won't be helpful, because the cells which > normally respond to erythropoietin by creating more red cells, can no > longer do so because the progenitor cells are damaged or dead and can > no longer produce red cells. > > Winstrol is known to be good for osteoporosis. My hypothesis is that > it strengthens the bone marrow by encouraging the growth of new cells > in the bone marrow. That would explain how red cell production gets > started back up again with the use of Winstrol. > > With the Epogen, it is causing more erythropoietin to be produced to > "tell" the progenitor cells to produce red cells, but the progenitor > cells are either dead or damaged by the virus and can no longer > respond appropriately to the detection of higher levels of > erythropoietin. Epogen might work if you start it before the bone > marrow is really devastated - ie - before you get the big drop in red > cells and haematocrit. > > Fair warning though: this is all my hypothesis, based on my own > observations, research and experience. > > Amani > -----Original Message----- > From: Felvtalk [mailto:felvtalk-boun...@felineleukemia.org] On Behalf > Of ROBERT CHAPEL > Sent: September-18-16 5:22 AM > To: felvtalk@felineleukemia.org > Cc: felvtalk@felineleukemia.org > Subject: Re: [Felvtalk] Epogen and other RBC enhancing drugs.... > > Wondering if anyone in the group has any experience with Epogen or > Procrit ( and other such RBC enhancing drugs typically used with > Kidney Failure patients)....?? It's appears to be quite a bit cheaper > when used for veterinary purposes than human....?? As the go to drug > for anemia in Kidney patients it would stand to reason that it " > should" work for Feline anemia......??? There will not be the same > resistance to using this as we encounter attempting to procure > Winstrol...... > > > ------------------------------ > > Subject: Digest Footer > > _______________________________________________ > Felvtalk mailing list > Felvtalk@felineleukemia.org > http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org > > > ------------------------------ > > End of Felvtalk Digest, Vol 29, Issue 21 > **************************************** > _______________________________________________ Felvtalk mailing list Felvtalk@felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org _______________________________________________ Felvtalk mailing list Felvtalk@felineleukemia.org http://felineleukemia.org/mailman/listinfo/felvtalk_felineleukemia.org
