Dear Dr. Isiegas: I envision neuroinformation as the mutual information of the neuronal network where synaptic connections are weighted by the frequencies of discharge between all pairs of neurons. This is directly analogous to a network of trophic exchanges among an ecosystem, as illustrated in <http://people.biology.ufl.edu/ulan/pubs/SymmOvhd.PDF>.
Please note that this measure is different from the conventional sender-channel-receiver format of communications theory. It resembles more the "structural information" inhering in the neuronal network. John Collier (also a FISer) calls such information "enformation" to draw attention to its different nature. With best wishes for success, Bob Ulanowicz > Dear list, > > I have been reading during the last year all these interesting > exchanges. Some of them terrific discussions! Given my scientific > backgound > (Molecular Neuroscience), I would like to hear your point of view on the > topic of neuroinformation, how information "exists" within the Central > Nervous Systems. My task was experimental; I was interested in > investigating the molecular mechanisms underlying learning and memory, > specifically, the role of the cAMP-PKA-CREB signaling pathway in such > brain > functions (In Ted Abel´s Lab at the University of Pennsylvania, where I > spent 7 years). I generated several genetically modified mice in which I > could regulate the expression of this pathway in specific brain regions > and > in which I studied the effects of upregulation or downregulation at the > synaptic and behavioral levels. However, I am conscious that the > "information flow" within the mouse Nervous System is far more complex > that > in the "simple" pathway that I was studying...so, my concrete question for > you "Fishers" or "Fisers", how should we contemplate the micro and macro > structures of information within the neural realm? what is > Neuroinformation? > > Best wishes, > > > -- > Carolina Isiegas > _______________________________________________ > Fis mailing list > Fis@listas.unizar.es > http://listas.unizar.es/cgi-bin/mailman/listinfo/fis > _______________________________________________ Fis mailing list Fis@listas.unizar.es http://listas.unizar.es/cgi-bin/mailman/listinfo/fis
