That did the trick, but I'm having trouble displaying the results.
First issue is that I can't seem to load my average surface in tksurfer from 
the command line.I get the following:

tksurfer average rh inflated
surfer: current subjects dir: /data/nelson/work/alex/freesurfer/subjects_twins
surfer: not in "scripts" dir ==> using cwd for session root
surfer: session root data dir ($session) set to:
surfer:     /data/nelson/work/alex/freesurfer/subjects_twins
ERROR: cound not stat 
/data/nelson/work/alex/freesurfer/subjects_twins/average/mri/T1/COR-.info.  
Does it exist?
mghRead(/data/nelson/work/alex/freesurfer/subjects_twins/average/mri/T1.mgh, 
-1): could not open file
zcat: /data/nelson/work/alex/freesurfer/subjects_twins/average/mri/T1.mgz.gz: 
No such file or directory
mghRead(/data/nelson/work/alex/freesurfer/subjects_twins/average/mri/T1.mgz, 
-1): read error
surfer: ### Could not find anatomical header information.

What I do instead is load a subject's surface and then click load > Surface, 
and select the average one. 
When I load the sigt file as an overlay, what should I specify as the 
registration matrix?
Clicking "calculate identity matrix" seems to work, so I'm assuming this is ok?

After doing this, I can visualize the SPM ok, but have trouble when I try to 
obtain scatterplots for a gven vertex. tksurfer closes and I get the error 
below.(I've tried specifying markers and colors in the FSGD but it doesn't seem 
to make a difference)
I'm using recon-all-nmr,v 1.104 2005/09/07.

 gdfReadHeader: reading 
/data/nelson/work/alex/freesurfer/subjects_twins/stats/twin_qualcheck_fsgd.txt
WARNING: Marker for class class_subj1 was invalid.
WARNING: Color for class class_subj1 was invalid.
WARNING: Marker for class class_subj2 was invalid.
WARNING: Color for class class_subj2 was invalid.
WARNING: Marker for class class_subj3 was invalid.
WARNING: Color for class class_subj3 was invalid.
WARNING: Marker for class class_subj4 was invalid.
WARNING: Color for class class_subj4 was invalid.
WARNING: Marker for class class_subj5 was invalid.
WARNING: Color for class class_subj5 was invalid.
surfer: dmin=0.8701, vno=132952, x=14.6850, y=-30.1178, z=47.7694
% surfer: curv=0.000000, fs=0.000000
% surfer: val=2.132707, val2=0.000000
% surfer: amp=2.132707, angle=0.000000 deg (0.000000)

Thanks again,
A


Oh, I'm sorry. I see the problem now. When I said to create a class
for each subject, I meant for each person, not for each FreeSurfer
subject. So there should only be 5 classes, not 10.

So do something like this:

Class class_subj1
Class class_subj2
Class class_subj3
Class class_subj4
Class class_subj5

Variables                       Time
Input time1_subj1 class_subj1   -1
Input time2_subj1 class_subj1   +1
...

doug

On Tue, 11 Apr 2006, Fornito, Alexander wrote:

> I still get the same error message. Maybe I've coded the variable wrong?
>
> gdfReadHeader: reading ./test_fsgd.txt
> INFO: gd2mtx_method is doss
> ERROR: Design Matrix: nrows (10) <= ncols (11)
>
>
>
> Alex Fornito
> M.Psych/PhD (clin. neuro.) candidate
> Melbourne Neuropsychiatry Centre and Department of Psychology
> National Neuroscience Facility
> The University of Melbourne
> Levels 2 & 3, Alan Gilbert Building
> 161 Barry St
> Carlton South Vic 3053 Australia
> Ph:    +61 3 8344 1624
> Fax:   +61 3 9348 0469
> email: [EMAIL PROTECTED]
>
>
>
> -----Original Message-----
> From: Doug Greve [mailto:[EMAIL PROTECTED]
> Sent: Tue 4/11/2006 11:43 AM
> To: Fornito, Alexander
> Cc: freesurfer@nmr.mgh.harvard.edu
> Subject: RE: [Freesurfer] Repeated-measures in mris_glm
>
>
> Yes, mris_preproc is new with stable. In your FSGD file, try
> specifying the title as a single string without spaces.
>
> doug
>
>
>
> On Tue, 11 Apr 2006, Fornito, Alexander wrote:
>
>> Hi Doug,
>> Is mri_preproc a new addition to the stable version? I'm using 
>> recon-all-nmr,v 1.104 2005/09/07 and can't seem to find it.
>> I tried running the analysis through mris_glm as per option 1 as you 
>> described, but came across a problem. Command, error, and my FSGD are below. 
>> Thanks,
>> Alex
>>
>> Command:
>>
>> mris_glm --surfmeas thickness --hemi lh --trgsubj ../average --fsgd 
>> ./test_fsgd.txt doss --beta ./beta_doss_thickness-100_lh bfloat --var 
>> ./var_doss_thickness-100_lh.w paint --y ./y_doss_thickness-100_lh_000.bfloat 
>> --nsmooth 100
>> gdfReadHeader: reading ./test_fsgd.txt
>> INFO: ignoring tag 1
>> INFO: gd2mtx_method is doss
>> ERROR: Design Matrix: nrows (10) <= ncols (11)
>>
>> My FSGD:
>>
>> GroupDescriptorFile 1
>> Title Time 1 vs Time 2
>> Class class_time1_subj1
>> Class class_time1_subj2
>> Class class_time1_subj3
>> Class class_time1_subj4
>> Class class_time1_subj5
>> Class class_time2_subj1
>> Class class_time2_subj2
>> Class class_time2_subj3
>> Class class_time2_subj4
>> Class class_time2_subj5
>> Variables                            Time
>> Input time1_subj1 class_time1_subj1  -1
>> Input time1_subj2 class_time1_subj2  -1
>> Input time1_subj3 class_time1_subj3  -1
>> Input time1_subj4 class_time1_subj4  -1
>> Input time1_subj5 class_time1_subj5  -1
>> Input time2_subj1 class_time2_subj1   1
>> Input time2_subj2 class_time2_subj2   1
>> Input time2_subj3 class_time2_subj3   1
>> Input time2_subj4 class_time2_subj4   1
>> Input time2_subj5 class_time2_subj5   1
>> DefaultVariable Time
>>
>> Alex Fornito
>> M.Psych/PhD (clin. neuro.) candidate
>> Melbourne Neuropsychiatry Centre and Department of Psychology
>> National Neuroscience Facility
>> The University of Melbourne
>> Levels 2 & 3, Alan Gilbert Building
>> 161 Barry St
>> Carlton South Vic 3053 Australia
>> Ph:    +61 3 8344 1624
>> Fax:   +61 3 9348 0469
>> email: [EMAIL PROTECTED]
>>
>>
>>
>> -----Original Message-----
>> From: Doug Greve [mailto:[EMAIL PROTECTED]
>> Sent: Tue 4/11/2006 9:31 AM
>> To: Fornito, Alexander
>> Cc: freesurfer@nmr.mgh.harvard.edu
>> Subject: Re: [Freesurfer] Repeated-measures in mris_glm
>>
>>
>> There are two ways to do it:
>>
>> 1. You can use DOSS, making each subject it's own class. Then create one
>> "Variable". For a given input, set the variable to either +1 or -1
>> depending upon whether it corresponds to  the first or second time
>> point. Then create a contrast as [0 0 0 0 ... 0 0 0 1], where there are
>> as many 0s as subjects. The last "1" will correspond to the Time Point
>> variable.
>>
>> 2. Alternatively, if you are using mris_preproc, you can specify
>> "--paired-diff", then just use a one-sample group mean test. See the
>> --help. This may be easier, and will also allow you to add a between
>> subject factor.
>>
>> doug
>>
>>
>> Fornito, Alexander wrote:
>>
>>> Hi,
>>> I'd like to run a simple repeated-measures analysis tetsing for change in 
>>> thickness measures between 2 time points. There is no between-subjects 
>>> factor, only the effect of time. Do I just set up a standard DOSS FSGD 
>>> file, or do I use a different format? The tutorial only covers 
>>> between-subjects designs.
>>> Thanks,
>>> Alex
>>>
>>>
>>>
>>> Alex Fornito
>>> M.Psych/PhD (clin. neuro.) candidate
>>> Melbourne Neuropsychiatry Centre and Department of Psychology
>>> National Neuroscience Facility
>>> The University of Melbourne
>>> Levels 2 & 3, Alan Gilbert Building
>>> 161 Barry St
>>> Carlton South Vic 3053 Australia
>>> Ph:    +61 3 8344 1624
>>> Fax:   +61 3 9348 0469
>>> email: [EMAIL PROTECTED]
>>>
>>>
>>>
>>>
>>> _______________________________________________
>>> Freesurfer mailing list
>>> Freesurfer@nmr.mgh.harvard.edu
>>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>>
>>>
>>>
>>>
>>
>>
>
>

-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
[EMAIL PROTECTED]
Phone Number: 617-724-2358 
Fax: 617-726-7422

In order to help us help you, please follow the steps in:
surfer.nmr.mgh.harvard.edu/fswiki/BugReporting



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