Hi,

For what it's worth, I have seen a very similar skull-strip failure on
at least one of my brains processed with Freesurfer 5.0 but not using
the -nuintensitycor-3T flag.  Happy to send data, if helpful.

Best.
Michael

On Wed, Feb 16, 2011 at 2:03 PM, Mehul Sampat <mpsam...@gmail.com> wrote:
> Hi Bruce,
>
> Okay. I will try it out 5.1 in the future and compare it to 4.5.
>
> I also have a question about comparisons between version 4.5 and 5.0
>
> In some cases, I saw that FS 4.5 does a slightly better job at skull
> stripping than FS 5.0.
> Esentially, FS 5.0 seems to make errors in the back of the brain and cuts
> out some tissue.
> (Please see attached images).
>
> The images are the same slice from the same subject processed with FS 4.5
> and 5.0 (This happens across 5-10 slices)
> In 5.0, I used the following command: recon-all -s "subj--id" -i
> "nifti-file" -all -nuintensitycor-3T
> (I have seen this issue in atleast 5 subjects in our data)
>
> Since 5.0 uses the graph cuts, could the error be due the combination of
> (graph cuts + -nuintensitycor-3T) ?
> Also, I guess I could run 5.0  and use only graph cuts or -nuintensitycor-3T
> to isolate the error ?
>
> Thanks
> Mehul
>
>
>
> On Tue, Feb 15, 2011 at 12:05 PM, Bruce Fischl <fis...@nmr.mgh.harvard.edu>
> wrote:
>>
>> Hi Mehul,
>>
>> I think 5.1 will work better for large ventricles than 4.5, but I'll be
>> interested to hear your experience.
>>
>> cheers
>> Bruce
>> On Tue, 15 Feb 2011, Mehul Sampat wrote:
>>
>>> Hi Bruce,
>>> We have two studies being conducted (one cross-sectional and one
>>> longitudinal)
>>> Some of the subjects in have a lot of atrophy and have large ventircles.
>>>
>>> For the cross-sectional analysis stream are there many differences
>>> between
>>> 4.5 and the forthcoming 5.1 ? Or would it be fine to use 4.5 for
>>> cross-sectional analysis ?
>>>
>>> (I understand that for the longitudinal study, I should wait for 5.1 and
>>> process all the timepoints with 5.1)
>>>
>>>
>>> Thanks
>>> Mehul
>>>
>>>
>>>
>>> On Thu, Jan 20, 2011 at 10:36 AM, Bruce Fischl
>>> <fis...@nmr.mgh.harvard.edu>wrote:
>>>
>>>> Hi Derin
>>>>
>>>> we are tracking down some issues with it and hope to have it out within
>>>> a
>>>> month
>>>>
>>>> cheers
>>>> Bruce
>>>> On Thu, 20 Jan 2011, Derin Cobia wrote:
>>>>
>>>>> All,
>>>>>
>>>>> Just curious about the current estimated timeline for version 5.1,
>>>>> trying
>>>>
>>>> to schedule some projects around it.  Thanks!
>>>>>
>>>>> -Derin
>>>>>
>>>>>
>>>>>
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>>>>>
>>>>>
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