Hi Fatima,

Your findings are not surprising. There is plenty of literature
describing problems with the VBM technique. You may read
e.g., Kennedy et al (2009), Neurobiology of Aging, vol. 10,
1657-1676 and references cited herein.

Ed

On 8 Jul 2011, at 15:02, [email protected] wrote:

>
> Hello,
>
> I'm wondering if anyone could help me out with a question I had. For  
> a study I'm working on, I'm comparing the regional brain volumes in  
> adolescents with and without PTSD. I ran VBM analysis and Freesurfer  
> on my subjects and I found some significant results on VBM (however,  
> only using uncorrected p values) and on Freesurfer, I found no group  
> differences in brain regions. Is there an explanation for that?
>
> If anyone has any thoughts I'd really appreciate it. Thank you kindly!
>
> Fatima

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