When I adjusted for the scale, the matrix is still ill-conditioned. It looks like some of the columns are very similar to each other. doug
On 06/12/2012 05:15 PM, mdkrue...@uwalumni.com wrote: > Hello- > > I am trying to analyze the cortical thickness between two groups of > subjects Cl1 and CL2. When i run the GLM i receive the error: > > matrix is ill-conditioned or badly scaled, condno = 1e+08 > > I am under the impression the error could be due to the > non-uniformity in the range/scale of the regressors. > > here is my information: > > contrast is 1 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 > > > 1) mri_glmfit --y lh.PvNPeverything.10.mgh --fsgd PvNPeverything.fsgd > dods --C PvNP_everything.mtx --surf UNM_ALLGOOD lh --cortex --glmdir > lh.PvNPeverything.glmdir > > 2) (sample of my fsgd) - there are no columns with all 0's in them > GroupDescriptorFile 1 > Title Methedone Comparison > Class Cl1 > Class Cl2 > Variables > WAISIQtrait_anxietyalcohol_yearheroin_yearcocaine_yearcannabis_yearmeth_yearamphetamines_yearmeth_amphet_yearhallucinogens_year > > > inhalants_yearmethodne_yearopiates_yearpills_yearopitates_pills_yearother_year > > total_years > InputM87160505Cl18633103911011180066049 > InputM87161888Cl11095900722000000000032 > InputM87107477Cl1893412091309961001910057 > InputM87199897Cl11174402301000000915015360 > InputM87146570Cl1944226038000000000637 > InputM87189755Cl111159110.52150331.500000036 > InputM87169696Cl18622201114000000000025 > InputM87187366Cl11065128027002020000000075 > InputM87178857Cl211748044805570400.080.08042.08 > InputM87165923Cl21034052015000000011023 > InputM87110556Cl21346040115000000000020 > InputM87183811Cl2974315083000000000026 > > 3) design matrix > > 1 0 86 0 33 0 10 0 3 0 > 9 0 11 0 0 0 1 0 1 0 > 1 0 8 0 0 0 0 0 6 0 > 6 0 0 0 49 0 > 1 0 109 0 59 0 0 0 0 0 > 7 0 22 0 0 0 0 0 0 0 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 32 0 > 1 0 89 0 34 0 12 0 0 0 > 9 0 13 0 0 0 9 0 9 0 > 6 0 10 0 0 0 1 0 9 0 > 10 0 0 0 57 0 > 1 0 89 0 40 0 15 0 5 0 > 2 0 30 0 10 0 0 0 > 10 0 2 0 0 0 0 0 0 0 > 0 0 0 0 0 0 59 0 > 1 0 77 0 44 0 0 0 0 0 > 3 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 3 0 > 1 0 91 0 22 0 6 0 0 0 > 3 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 8 0 > 1 0 103 0 29 0 20 0 3 0 > 11 0 27 0 0 0 11 0 > 11 0 5 0 0 0 0 0 0 0 > 1 0 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0 > 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 0 0 > 0 1 0 109 0 28 0 3 0 0 > 0 2 0 2 0 0 0 0 0 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 0 5 > 0 1 0 91 0 27 0 20 0 0 > 0 15 0 0 0 3 0 0 0 3 > 0 0 0 0 0 0 0 17 0 0 > 0 17 0 0 0 55 > 0 1 0 89 0 48 0 9 0 0 > 0 0.25 0 10 0 20 0 0 0 > 20 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 0 39.25 > 0 1 0 97 0 28 0 10 0 0 > 0 4 0 10 0 5 0 0 0 5 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 29 > 0 1 0 100 0 40 0 3 0 0 > 0 0 0 0.17 0 0 0 0 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 0 0 3.17 > 0 1 0 89 0 21 0 20 0 8 > 0 25 0 25 0 10 0 0 0 > 10 0 0 0 2 0 0 0 0 0 > 0 0 0 0 0 0 90 > 0 1 0 103 0 54 0 10 0 0 > 0 2 0 0 0 0 0 2 0 2 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 12 > 0 1 0 77 0 49 0 0 0 0 > 0 10 0 12 0 0 0 4 0 4 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 2 0 42 > 0 1 0 89 0 42 0 0 0 0 > 0 4 0 10 0 0 0 0 0 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 0 14 > 0 1 0 117 0 34 0 25 0 0 > 0 2 0 25 0 0 0 0 0 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 0 52 > 0 1 0 83 0 56 0 12 0 0 > 0 0 0 15 0 0 0 0 0 0 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 15 > 0 1 0 91 0 33 0 0 0 0 > 0 0 0 2 0 0 0 0 0 0 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 2 > 0 1 0 106 0 36 0 0 0 0 > 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 0 0 > 0 1 0 120 0 50 0 1 0 0 > 0 0 0 2 0 1 0 0 0 > 1 0 0 0 0 0 0 0 0 0 > 0 0 0 0 0 0 6 > > > -- > Michael D. Kruepke > PhD - University of Illinois at Urbana-Champaign > BA - Psych - University of Wisconsin-Madison > mdkrue...@gmail.com <mailto:mdkrue...@gmail.com> > (262)-483-7449 > > > > _______________________________________________ > Freesurfer mailing list > Freesurfer@nmr.mgh.harvard.edu > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer -- Douglas N. Greve, Ph.D. MGH-NMR Center gr...@nmr.mgh.harvard.edu Phone Number: 617-724-2358 Fax: 617-726-7422 Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting FileDrop: www.nmr.mgh.harvard.edu/facility/filedrop/index.html _______________________________________________ Freesurfer mailing list Freesurfer@nmr.mgh.harvard.edu https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The information in this e-mail is intended only for the person to whom it is addressed. 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