Hello,

I am using mri_glmfit to perform a correlation analysis between some 
surface-based DTI measures and a behavioural outcome (grip), aiming to 
correct for scannertyp (C,I,W), handedness (R,L) as discrete variables and 
age (AGE) and duration (Mo) as continuous covariates. Please find the fsgd 
file, the contrast file and the calculated Xg down below.
However, I get the follow error:

DOF = -10
ERROR: DOF = -10 (the complete output is attached)

I would be grateful if somebody could help. I already tried it with demeaned 
data, z-transformed data, it doesn't help.

Thank you for your help,

Robert


========================================

fsgd file:
GroupDescriptorFile 1
Title OSGM
Class CR
Class CL
Class WL
Class WR
Class IR
Class IL
Variables Age Mo Grip
Input c02 CR 52 85 0.250
Input c04 CR 71 27 0.652
Input c05 CL 63 12 0.788
Input c06 WL 77 26 0.438
Input c07 WR 61 13 0.717
Input c10 IR 68 9 0.730
Input c11 IL 63 13 0.934
Input c12 IL 29 12 1.170
Input c13 IR 46 12 0.964
Input c14 IR 75 14 0.655
Input c15 IL 68 13 1.098
Input c16 IR 69 12 1.028
Input c18 WL 40 20 0.698
Input c19 WL 53 13 0.547

contrast file:
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 1 1

design matrix:

+1.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +52.00000 +0.00000 
+0.00000 +0.00000 +0.00000 +0.00000 +85.00000 +0.00000 +0.00000 +0.00000 
+0.00000 +0.00000 +0.25000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000
+1.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +71.00000 +0.00000 
+0.00000 +0.00000 +0.00000 +0.00000 +27.00000 +0.00000 +0.00000 +0.00000 
+0.00000 +0.00000 +0.65200 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000
+0.00000 +1.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +63.00000 
+0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +12.00000 +0.00000 +0.00000 
+0.00000 +0.00000 +0.00000 +0.78800 +0.00000 +0.00000 +0.00000 +0.00000
+0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 
+77.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +26.00000 +0.00000 
+0.00000 +0.00000 +0.00000 +0.00000 +0.43800 +0.00000 +0.00000 +0.00000
+0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 +0.00000 
+0.00000 +61.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +13.00000 
+0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.71700 +0.00000 +0.00000
+0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 
+0.00000 +0.00000 +68.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 
+9.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.73000 +0.00000
+0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 
+0.00000 +0.00000 +0.00000 +63.00000 +0.00000 +0.00000 +0.00000 +0.00000 
+0.00000 +13.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.93400
+0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 
+0.00000 +0.00000 +0.00000 +29.00000 +0.00000 +0.00000 +0.00000 +0.00000 
+0.00000 +12.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +1.17000
+0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 
+0.00000 +0.00000 +46.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 
+12.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.96400 +0.00000
+0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 
+0.00000 +0.00000 +75.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 
+14.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.65500 +0.00000
+0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 
+0.00000 +0.00000 +0.00000 +68.00000 +0.00000 +0.00000 +0.00000 +0.00000 
+0.00000 +13.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +1.09800
+0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 
+0.00000 +0.00000 +69.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 
+12.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +1.02800 +0.00000
+0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 
+40.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +20.00000 +0.00000 
+0.00000 +0.00000 +0.00000 +0.00000 +0.69800 +0.00000 +0.00000 +0.00000
+0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 
+53.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +13.00000 +0.00000 
+0.00000 +0.00000 +0.00000 +0.00000 +0.54700 +0.00000 +0.00000 +0.00000

output:

gdfReadHeader: reading 
/home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l/glmout/corr.fsgd
INFO: DeMeanFlag keyword not found, DeMeaning will NOT be done.
Continuous Variable Means (all subjects)
0 Age 59.6429 13.4462
1 Mo 20.0714 18.7444
2 Grip 0.762071 0.248599
Class Means of each Continuous Variable
1 CR 61.5000 56.0000 0.4510
2 CL 63.0000 12.0000 0.7880
3 WL 56.6667 19.6667 0.5610
4 WR 61.0000 13.0000 0.7170
5 IR 64.5000 11.7500 0.8442
6 IL 53.3333 12.6667 1.0673
INFO: gd2mtx_method is dods
Reading source surface 
/home/schulz/freesurfer/subjects/premotorstroke/fsaverage/surf/lh.white
Number of vertices 163842
Number of faces 327680
Total area 65416.648438
AvgVtxArea 0.399267
AvgVtxDist 0.721953
StdVtxDist 0.195470
$Id: mri_glmfit.c,v 1.196.2.6 2011/05/05 20:54:25 greve Exp $
cwd /home/schulz/dti/premotorstroke/02
cmdline mri_glmfit --glmdir 
/home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l --y 
/home/schulz/dti/premotorstroke/wm-probe/fs_no3/l_average_all_smooth.mgh --fsgd 
/home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l/glmout/corr.fsgd 
 --C 
/home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l/glmout/corr.mtx 
 --surf fsaverage lh --cortex
sysname Linux
hostname BINS-Linux1
machine x86_64
user schulz
FixVertexAreaFlag = 1
UseMaskWithSmoothing 1
OneSampleGroupMean 0
y /home/schulz/dti/premotorstroke/wm-probe/fs_no3/l_average_all_smooth.mgh
logyflag 0
usedti 0
FSGD 
/home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l/glmout/corr.fsgd
labelmask 
/home/schulz/freesurfer/subjects/premotorstroke/fsaverage/label/lh.cortex.label
maskinv 0
glmdir /home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l
IllCondOK 0
ReScaleX 1
DoFFx 0
Creating output directory 
/home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l
Loading y from 
/home/schulz/dti/premotorstroke/wm-probe/fs_no3/l_average_all_smooth.mgh
INFO: gd2mtx_method is dods
Saving design matrix to 
/home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l/Xg.dat
Normalized matrix condition is 1420.61
Matrix condition is 954196
Found 149955 points in label.
Pruning voxels by thr: 0.000000
Found 136331 voxels in mask
Saving mask to 
/home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l/mask.mgh
Reshaping mriglm->mask...
search space = 67992.449783
DOF = -10
ERROR: DOF = -10



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_____________________________________________________________________

Universitätsklinikum Hamburg-Eppendorf; Körperschaft des öffentlichen Rechts; 
Gerichtsstand: Hamburg
Vorstandsmitglieder: Prof. Dr. Martin Zeitz (Vorsitzender), Prof. Dr. Dr. Uwe 
Koch-Gromus, Joachim Prölß, Rainer Schoppik
_____________________________________________________________________

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