It usually means that the number of subjects in the input is less (10 
less) than the number of regressors. It looks like you have about 14 
input subjects and 24=6*4 regressors. You need to add subjects or remove 
regressors (ie, classes or covariates)
doug

On 9/18/13 11:41 AM, Robert Schulz wrote:
> Hello,
>
> I am using mri_glmfit to perform a correlation analysis between some
> surface-based DTI measures and a behavioural outcome (grip), aiming to
> correct for scannertyp (C,I,W), handedness (R,L) as discrete variables and
> age (AGE) and duration (Mo) as continuous covariates. Please find the fsgd
> file, the contrast file and the calculated Xg down below.
> However, I get the follow error:
>
> DOF = -10
> ERROR: DOF = -10 (the complete output is attached)
>
> I would be grateful if somebody could help. I already tried it with demeaned
> data, z-transformed data, it doesn't help.
>
> Thank you for your help,
>
> Robert
>
>
> ========================================
>
> fsgd file:
> GroupDescriptorFile 1
> Title OSGM
> Class CR
> Class CL
> Class WL
> Class WR
> Class IR
> Class IL
> Variables Age Mo Grip
> Input c02 CR 52 85 0.250
> Input c04 CR 71 27 0.652
> Input c05 CL 63 12 0.788
> Input c06 WL 77 26 0.438
> Input c07 WR 61 13 0.717
> Input c10 IR 68 9 0.730
> Input c11 IL 63 13 0.934
> Input c12 IL 29 12 1.170
> Input c13 IR 46 12 0.964
> Input c14 IR 75 14 0.655
> Input c15 IL 68 13 1.098
> Input c16 IR 69 12 1.028
> Input c18 WL 40 20 0.698
> Input c19 WL 53 13 0.547
>
> contrast file:
> 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 1 1
>
> design matrix:
>
> +1.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +52.00000 +0.00000
> +0.00000 +0.00000 +0.00000 +0.00000 +85.00000 +0.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +0.25000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +1.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +71.00000 +0.00000
> +0.00000 +0.00000 +0.00000 +0.00000 +27.00000 +0.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +0.65200 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +63.00000
> +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +12.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +0.00000 +0.78800 +0.00000 +0.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +77.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +26.00000 +0.00000
> +0.00000 +0.00000 +0.00000 +0.00000 +0.43800 +0.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +0.00000 +61.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +13.00000
> +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.71700 +0.00000 +0.00000
> +0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +68.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +9.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.73000 +0.00000
> +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +0.00000 +63.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +0.00000 +13.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.93400
> +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +0.00000 +29.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +0.00000 +12.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +1.17000
> +0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +46.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +12.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.96400 +0.00000
> +0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +75.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +14.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.65500 +0.00000
> +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +0.00000 +68.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +0.00000 +13.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +1.09800
> +0.00000 +0.00000 +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +69.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +12.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +1.02800 +0.00000
> +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +40.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +20.00000 +0.00000
> +0.00000 +0.00000 +0.00000 +0.00000 +0.69800 +0.00000 +0.00000 +0.00000
> +0.00000 +0.00000 +1.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000
> +53.00000 +0.00000 +0.00000 +0.00000 +0.00000 +0.00000 +13.00000 +0.00000
> +0.00000 +0.00000 +0.00000 +0.00000 +0.54700 +0.00000 +0.00000 +0.00000
>
> output:
>
> gdfReadHeader: reading
> /home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l/glmout/corr.fsgd
> INFO: DeMeanFlag keyword not found, DeMeaning will NOT be done.
> Continuous Variable Means (all subjects)
> 0 Age 59.6429 13.4462
> 1 Mo 20.0714 18.7444
> 2 Grip 0.762071 0.248599
> Class Means of each Continuous Variable
> 1 CR 61.5000 56.0000 0.4510
> 2 CL 63.0000 12.0000 0.7880
> 3 WL 56.6667 19.6667 0.5610
> 4 WR 61.0000 13.0000 0.7170
> 5 IR 64.5000 11.7500 0.8442
> 6 IL 53.3333 12.6667 1.0673
> INFO: gd2mtx_method is dods
> Reading source surface
> /home/schulz/freesurfer/subjects/premotorstroke/fsaverage/surf/lh.white
> Number of vertices 163842
> Number of faces 327680
> Total area 65416.648438
> AvgVtxArea 0.399267
> AvgVtxDist 0.721953
> StdVtxDist 0.195470
> $Id: mri_glmfit.c,v 1.196.2.6 2011/05/05 20:54:25 greve Exp $
> cwd /home/schulz/dti/premotorstroke/02
> cmdline mri_glmfit --glmdir
> /home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l --y
> /home/schulz/dti/premotorstroke/wm-probe/fs_no3/l_average_all_smooth.mgh 
> --fsgd
> /home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l/glmout/corr.fsgd
>   --C
> /home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l/glmout/corr.mtx
>   --surf fsaverage lh --cortex
> sysname Linux
> hostname BINS-Linux1
> machine x86_64
> user schulz
> FixVertexAreaFlag = 1
> UseMaskWithSmoothing 1
> OneSampleGroupMean 0
> y /home/schulz/dti/premotorstroke/wm-probe/fs_no3/l_average_all_smooth.mgh
> logyflag 0
> usedti 0
> FSGD
> /home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l/glmout/corr.fsgd
> labelmask
> /home/schulz/freesurfer/subjects/premotorstroke/fsaverage/label/lh.cortex.label
> maskinv 0
> glmdir /home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l
> IllCondOK 0
> ReScaleX 1
> DoFFx 0
> Creating output directory
> /home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l
> Loading y from
> /home/schulz/dti/premotorstroke/wm-probe/fs_no3/l_average_all_smooth.mgh
> INFO: gd2mtx_method is dods
> Saving design matrix to
> /home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l/Xg.dat
> Normalized matrix condition is 1420.61
> Matrix condition is 954196
> Found 149955 points in label.
> Pruning voxels by thr: 0.000000
> Found 136331 voxels in mask
> Saving mask to
> /home/schulz/dti/premotorstroke/wm-probe/fs_no3/glmout_corr_l/mask.mgh
> Reshaping mriglm->mask...
> search space = 67992.449783
> DOF = -10
> ERROR: DOF = -10
>
>
>
> --
>
> Besuchen Sie uns auf: www.uke.de
> _____________________________________________________________________
>
> Universitätsklinikum Hamburg-Eppendorf; Körperschaft des öffentlichen Rechts; 
> Gerichtsstand: Hamburg
> Vorstandsmitglieder: Prof. Dr. Martin Zeitz (Vorsitzender), Prof. Dr. Dr. Uwe 
> Koch-Gromus, Joachim Prölß, Rainer Schoppik
> _____________________________________________________________________
>
> SAVE PAPER - THINK BEFORE PRINTING
>
>
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