Apologies.

forwarded it on now

Thanks a million

Erik

Dr. Erik O'Hanlon PhD MSc BScEng
Post Doctoral Researcher


RCSI Psychiatry
Royal College of Surgeons in Ireland
Beaumont Road, Beaumont, D9, Ireland
T: 8093740
E: erikohan...@rcsi.ie  W: www.rcsi.ie

RCSI DEVELOPING HEALTHCARE LEADERS
WHO MAKE A DIFFERENCE WORLDWIDE
________________________________________
From: Bruce Fischl [fis...@nmr.mgh.harvard.edu]
Sent: 02 April 2014 19:58
To: Erik O'Hanlon
Subject: Re: [Freesurfer] FW: registration difficulty

Hi Erik

can you cc the list so that others (like Doug!) can respond?

thanks
Bruce
On Wed, 2 Apr
2014, Erik O'Hanlon wrote:

>
> Hi Bruce,
>
> Thanks so much for your reply. As for the specifics of what I have tried, so
> rry if it was unclear.
>
> I have performed the usual T1 based FS cortical and subcortical analysis and
>  included the -hip_subfields so I also get all the subdivision volumes. I ha
> ve also run a DWI analysis in ExploreDTI and now want to use the subfield vo
> lumes as masks for the purpose of tractography. I created my diff-to-orig da
> t file using bbregister. I then used this in the mri_vol2vol and aligned my
> aseg.mgz to my nodif image. This worked really well and I then used fslmaths
>  to extract out the hippocampus from the aseg2diff. This aligns nicely. I th
> en tried to apply the same transformation to my subfield volumes but this di
> dn't work. As you suggested, and just to clarify,
>
> should I now rerun the bbregsiter and create a new dat file for the subfield
>  volume to orig.mgz image? Do I then use this in the mri_vol2vol and align m
> y subfield volume to the orig.mgz and then run a second mri_vol2vol but use
> the nodif2orig.dat calculated before and use the nodif image as the --mov fi
> le and the registered subfield_2orig.nii  as the --targ and use the --inv --
> nearest settings as I want end up with my subfield volumes in diffusion spac
> e ?
>
> So sorry for the confusion, really shows my lack of experience with FS. Just
>  getting completely mixed up at this stage.
>
> Again apologies for the lack of clarity and confusion but any pointers offer
> ed would be fantastic.
>
> Thanks again
>
> best regards
>
> Erik
>
> __________________________________________________________________
>
> Hi Erik
>
> so you had a separate (presumably highres) acquisition within the
> hippocampus? Have you registered that with bbregister? Your best bet is
> probably doing so, then composing the two registrations (and inverting one,
> depending on what direction you want to go).
>
> cheers
> Bruce
>
>
>
> On Wed, 2 Apr 2014, Erik O'Hanlon wrote:
>
> >
> >
> > Dear FS experts,
> >
> > I am running my first FS analysis and I'm trying to register my hippocampa
> l
> > subdivision volumes to my diffusion space image but cannot get good
> > alignment. I ran my diffusion preprocessing in ExploreDTI so don't have th
> e
> > register.dat file automatically so created this using the bbregister tool
> and
> > registered B0 image to my orig.mgz. I then used this dat to align my aseg
> to
> > my diffusion space image and it worked well. The issue is when I try to us
> e
> > it to transform my hippocampal subfield volumes to diffusion space. They j
> ust
> > don't line up. Is this due to the different FOV for the subfields? Can any
> one
> > advise how to get these volumes to transform correctly?
> >
> > Any help would be greatly appreciated.
> >
> > Thanks
> >
> > Erik
>
> Dr. Erik O'Hanlon PhD MSc BScEng
> Post Doctoral Researcher
>
> [IMAGE]
>
> RCSI Psychiatry
> Royal College of Surgeons in Ireland
> Beaumont Road, Beaumont, D9, Ireland
> T: 8093740
> E: erikohan...@rcsi.ie  W: www.rcsi.ie
>
> RCSI DEVELOPING HEALTHCARE LEADERS
> WHO MAKE A DIFFERENCE WORLDWIDE
>
>
>
>


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