The cache is not set up for volume-based analysis. There are two options:

1. use gaussian random fields (--grf instead of --cache). If you want to 
use this option, let me know as I have recently made some changes to it 
that make it more accurate

2. use permutation (--perm 5000 1.3 pos). This method is probably better 
given the problems in the Eklund, 2016, PNAS paper


doug


On 10/20/2016 09:20 PM, John Anderson wrote:
> Dear Doug,
> Thank you very much for this detailed explaination. I highly 
> appreciate your help
> Kindly I have the following question:
> The command mri_vol2vol ran smoothly without any errors
> The command mri_mask output the following :
> mri_mask suvr.tal2mm.nii 
> $FREESURFER_HOME/subjects/fsaverage/mri.2mm/subcort.mask.mgz 
> suvr.tal2mm.subc.nii
> freadFloat: fread failed
> DoAbs = 0
> Writing masked volume to suvr.tal2mm.subc.nii...done.
> Should I worry about this error ?
> I ignored this error and I continued the following steps. They went 
> fine but when I correct for multiple comparisons using the command 
> "mri_glmfit-sim" I get the following:
> mri_glmfit-sim --glmdir subc.glmdir --cache 1.3 pos --cwp 0.05 --3spaces
> cmdline mri_glmfit --y all.pet.tal2mm.subc.sm5.nii --fsgd fsgd.dat --C 
> 2G0C.mtx --glmdir subc.glmdir
> log file is subc.glmdir/cache.mri_glmfit-sim.log
> cd /analyses/pet_scan/SBM/sm
> /usr/local/freesurfer/stable5_3_0/bin/mri_glmfit-sim
> --glmdir subc.glmdir --cache 1.3 pos --cwp 0.05 --3spaces
> $Id: mri_glmfit-sim,v 1.36.2.5 2012/10/01 22:31:37 greve Exp $
> Thu Oct 20 21:10:31 EDT 2016
> Linux sven 2.6.32-642.3.1.el6.x86_64 #1 SMP Tue Jul 12 18:30:56 UTC 
> 2016 x86_64 x86_64 x86_64 GNU/Linux
> malshikh
> setenv SUBJECTS_DIR /analyses/recons
> FREESURFER_HOME /usr/local/freesurfer/stable5_3_0
> Original mri_glmfit command line:
> cmdline mri_glmfit --y all.pet.tal2mm.subc.sm5.nii --fsgd fsgd.dat --C 
> 2G0C.mtx --glmdir subc.glmdir
> DoSim = 0
> UseCache = 1
> DoPoll = 0
> DoPBSubmit = 0
> DoBackground = 0
> DiagCluster = 0
> gd2mtx = dods
> fwhm = 10.682767
> ERROR: cannot find 
> /usr/local/freesurfer/stable5_3_0/average/mult-comp-cor///cortex/fwhm11/pos/th13/mc-z.csd
> I smoothed just fwhm = 1
> Kindly how can I troubleshoo? thank you for any advice
> Bests,
> John
> *Sent:* Thursday, October 20, 2016 at 12:16 PM
> *From:* "Douglas N Greve" <gr...@nmr.mgh.harvard.edu>
> *To:* freesurfer@nmr.mgh.harvard.edu
> *Subject:* Re: [Freesurfer] surface based analysis for subcortical 
> structures
>
> After spmregister, you can run
>
> mri_vol2vol --mov pet.nii --reg reg.dat --tal --talres 2 --talxfm
> talairach.xfm --nearest --no-save-reg --o pet.tal2mm.nii
>
> # mask out the cortical structures
>
> mri_mask pet.tal2mm.nii
> $FREESURFER_HOME/subjects/fsaverage/mri.2mm/subcort.mask.mgz
> pet.tal2mm.subc.nii
>
> # Concatenate all subjects together
>
> mri_concat s1/pet.tal2mm.subc.nii s2/pet.tal2mm.subc.nii ... --o
> all.pet.tal2mm.subc.nii --prune
>
> # smooth
>
> mri_fwhm --i all.pet.tal2mm.subc.nii --mask
> $FREESURFER_HOME/subjects/fsaverage/mri.2mm/subcort.mask.mgz --fwhm X
> --smooth-only --o all.pet.tal2mm.subc.smoothed.nii
>
> mri_glmfit --y all.pet.tal2mm.subc.smoothed.nii --fsgd fsgd.txt--C
> 2gc0.mtx --glmdir subc.glmdir
>
>
>
> On 10/19/2016 05:09 PM, John Anderson wrote:
> > Dear experts,
> > I ran surface based analysis using PET maps. As the following:
> > spmregister --s subj --mov pet.nii --reg reg.dat --out pet_t1.mgh
> > mris_preproc --target fsaverage --hemi lh --iv subj1/ubject1_pet.nii 
> subject1/pet/pet_2_T1_register.dat ..... --projfrac 0.5 --out lh.mgh
> > mri_surf2surf --hemi lh --s fsaverage --fwhm 6 --cortex --sval 
> lh.mgh --tval lh.sm6.mgh
> > mri_glmfit--y lh.sm6.mgh--fsgd fsgd.txt--C 2gc0.mtx --surf fsaverage 
> lh --cortex --glmdir lh.glmdir//
> > then mri_glmfit-sim to correct for multiple comparison.
> > I want to study the subcortical regions and map it on MNI305. How can
> > I resume tha analysis for subcortical structures?
> > Thank you for any help!
> > Bests,
> > John
> >
> >
> > _______________________________________________
> > Freesurfer mailing list
> > Freesurfer@nmr.mgh.harvard.edu
> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>
> --
> Douglas N. Greve, Ph.D.
> MGH-NMR Center
> gr...@nmr.mgh.harvard.edu
> Phone Number: 617-724-2358
> Fax: 617-726-7422
>
> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
> www.nmr.mgh.harvard.edu/facility/filedrop/index.html 
> <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>
> Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>
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-- 
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

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