Hi Doug,
I have one additional question regarding surface based analyses:
Let's say that we have two types of brain lesions:
1. The first one is located in the cortical parcellates ( the labels in freesurfer atlas (wmparc.mgz) are named ctx-lh-? and ctx-rh-?).
2. The second lesion is located in the white matter parcellates ( the labels in freesurfer atlas (wmparc.mgz) are named  wm-lh-? and wm-rh-?).
 
Depedning on the location of these lesions the study subjects are divided into three groups ( normal people, those who have lesions in the cortical parcellates and those who have lesions in the white matter parcellates)
 
I want to invistigate the position of these lesions by runnig two surface based analyses (using PET images and the pipelines mentioned bellow) to show the location of these lesions (superfecial and deeper):
1. The first surface based analysis is between normal people and those who have supperfecial lesions in the cortical parcellates
2. The second surface based analysis is betweem normal people and those who have deep lesions in the white matter parcellates
 
In this case can the surface based analysis be able to find these differnces (between lesions in the cortical parcellates vs lesions in the white matter parcellates) using the same projection factor? Or I need to change the projection factor to include more deeper structures in the analysis?
 
Thank you for any advice!
John
 
Sent: Monday, November 14, 2016 at 1:29 PM
From: "John Anderson" <j.ander...@publicist.com>
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] Fw: Re: surface based analysis for subcortical structures
Thank you very much Doug. You are so awsome :)
 
Bests,
John Anderson

Senior Research Associate
Psychological and Brain Sciences Dept.
Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH 03755
Phone: +1 (603) 646-9834
Fax: +1 (603) 646-1419
 
 
Sent: Monday, November 14, 2016 at 1:00 PM
From: "Douglas N Greve" <gr...@nmr.mgh.harvard.edu>
To: freesurfer@nmr.mgh.harvard.edu
Subject: Re: [Freesurfer] Fw: Re: surface based analysis for subcortical structures
Hi, I just found a bug in mri_glmfit-sim in regards to GRF on
volume-based data. I put a fixed version at the same location. Please
use the new version


On 11/04/2016 10:25 AM, Douglas N Greve wrote:
> oops, sorry,
>
> download these files
>
> https://gate.nmr.mgh.harvard.edu/safelinks/greve/mri_glmfit-sim
>
> https://gate.nmr.mgh.harvard.edu/safelinks/greve/mri_volcluster
>
> https://gate.nmr.mgh.harvard.edu/safelinks/greve/mri_surfcluster
>
> Copy them into $FREESURFER_HOME/bin (after making a backup of the
> previous files).
>
> Edit mri_glmfit-sim to remove
>
> source $FREESURFER_HOME/sources.csh
>
> then hopefully everything should work
>
> doug
>
>
> On 11/04/2016 06:11 AM, John Anderson wrote:
>> Hi Doug,
>> I want to use GRF. Will you be willing to share the new versions of
>> the programs? Your help is highly appreciated.
>> Thanks!
>> Jon
>> *on:* Friday, October 28, 2016 at 11:53 AM
>> *From:* "Douglas Greve" <gr...@nmr.mgh.harvard.edu>
>> *To:* freesurfer@nmr.mgh.harvard.edu
>> *Subject:* Re: [Freesurfer] Fw: Re: surface based analysis for
>> subcortical structures
>>
>> If you want to use GRF, then I should get you new versions of some of
>> the programs as the volume-based GRF used the Friston 1994 algorithm
>> that was not as accurate as the Worsley 1996 algorithm. I just
>> updated my code last week (better late than never:). But in the end,
>> you probably want to use permutation if your group analysis allows it.
>>
>> On 10/23/16 10:25 AM, John Anderson wrote:
>>
>> Thank you very much Doug,
>> The codes worked very well. I was using the wrong command to
>> correct the data.
>> My command was
>> mri_glmfit-sim --glmdir subc.glmdir --cache 1.3 pos --cwp 0.05
>> --3spaces
>> and for subcortical structures it must be
>>
>> mri_glmfit-sim --glmdir subc.glmdir --grf 3 pos --cwpvalthresh .0166
>>
>> All the bests,
>> John Anderson
>>
>> Senior Research Associate
>> Psychological and Brain Sciences Dept.
>> Dartmouth College, 419 Moore Hall, Hinman Box 6207, Hanover, NH
>> 03755
>> Phone: +1 (603) 646-9834
>> Fax: +1 (603) 646-1419
>> *Sent:* Thursday, October 20, 2016 at 9:20 PM
>> *From:* "John Anderson" <j.ander...@publicist.com>
>> *To:* freesurfer@nmr.mgh.harvard.edu
>> *Subject:* Re: [Freesurfer] surface based analysis for subcortical
>> structures
>> Dear Doug,
>> Thank you very much for this detailed explaination. I highly
>> appreciate your help
>> Kindly I have the following question:
>> The command mri_vol2vol ran smoothly without any errors
>> The command mri_mask output the following :
>> mri_mask suvr.tal2mm.nii
>> $FREESURFER_HOME/subjects/fsaverage/mri.2mm/subcort.mask.mgz
>> suvr.tal2mm.subc.nii
>> freadFloat: fread failed
>> DoAbs = 0
>> Writing masked volume to suvr.tal2mm.subc.nii...done.
>> Should I worry about this error ?
>> I ignored this error and I continued the following steps. They
>> went fine but when I correct for multiple comparisons using the
>> command "mri_glmfit-sim" I get the following:
>> mri_glmfit-sim --glmdir subc.glmdir --cache 1.3 pos --cwp 0.05
>> --3spaces
>> cmdline mri_glmfit --y all.pet.tal2mm.subc.sm5.nii --fsgd fsgd.dat
>> --C 2G0C.mtx --glmdir subc.glmdir
>> log file is subc.glmdir/cache.mri_glmfit-sim.log
>> cd /analyses/pet_scan/SBM/sm
>> /usr/local/freesurfer/stable5_3_0/bin/mri_glmfit-sim
>> --glmdir subc.glmdir --cache 1.3 pos --cwp 0.05 --3spaces
>> $Id: mri_glmfit-sim,v 1.36.2.5 2012/10/01 22:31:37 greve Exp $
>> Thu Oct 20 21:10:31 EDT 2016
>> Linux sven 2.6.32-642.3.1.el6.x86_64 #1 SMP Tue Jul 12 18:30:56
>> UTC 2016 x86_64 x86_64 x86_64 GNU/Linux
>> malshikh
>> setenv SUBJECTS_DIR /analyses/recons
>> FREESURFER_HOME /usr/local/freesurfer/stable5_3_0
>> Original mri_glmfit command line:
>> cmdline mri_glmfit --y all.pet.tal2mm.subc.sm5.nii --fsgd fsgd.dat
>> --C 2G0C.mtx --glmdir subc.glmdir
>> DoSim = 0
>> UseCache = 1
>> DoPoll = 0
>> DoPBSubmit = 0
>> DoBackground = 0
>> DiagCluster = 0
>> gd2mtx = dods
>> fwhm = 10.682767
>> ERROR: cannot find
>> /usr/local/freesurfer/stable5_3_0/average/mult-comp-cor///cortex/fwhm11/pos/th13/mc-z.csd
>> I smoothed just fwhm = 1
>> Kindly how can I troubleshoo? thank you for any advice
>> Bests,
>> John
>> *Sent:* Thursday, October 20, 2016 at 12:16 PM
>> *From:* "Douglas N Greve" <gr...@nmr.mgh.harvard.edu>
>> *To:* freesurfer@nmr.mgh.harvard.edu
>> *Subject:* Re: [Freesurfer] surface based analysis for subcortical
>> structures
>>
>> After spmregister, you can run
>>
>> mri_vol2vol --mov pet.nii --reg reg.dat --tal --talres 2 --talxfm
>> talairach.xfm --nearest --no-save-reg --o pet.tal2mm.nii
>>
>> # mask out the cortical structures
>>
>> mri_mask pet.tal2mm.nii
>> $FREESURFER_HOME/subjects/fsaverage/mri.2mm/subcort.mask.mgz
>> pet.tal2mm.subc.nii
>>
>> # Concatenate all subjects together
>>
>> mri_concat s1/pet.tal2mm.subc.nii s2/pet.tal2mm.subc.nii ... --o
>> all.pet.tal2mm.subc.nii --prune
>>
>> # smooth
>>
>> mri_fwhm --i all.pet.tal2mm.subc.nii --mask
>> $FREESURFER_HOME/subjects/fsaverage/mri.2mm/subcort.mask.mgz
>> --fwhm X
>> --smooth-only --o all.pet.tal2mm.subc.smoothed.nii
>>
>> mri_glmfit --y all.pet.tal2mm.subc.smoothed.nii --fsgd fsgd.txt--C
>> 2gc0.mtx --glmdir subc.glmdir
>>
>>
>>
>> On 10/19/2016 05:09 PM, John Anderson wrote:
>> > Dear experts,
>> > I ran surface based analysis using PET maps. As the following:
>> > spmregister --s subj --mov pet.nii --reg reg.dat --out pet_t1.mgh
>> > mris_preproc --target fsaverage --hemi lh --iv
>> subj1/ubject1_pet.nii subject1/pet/pet_2_T1_register.dat .....
>> --projfrac 0.5 --out lh.mgh
>> > mri_surf2surf --hemi lh --s fsaverage --fwhm 6 --cortex --sval
>> lh.mgh --tval lh.sm6.mgh
>> > mri_glmfit--y lh.sm6.mgh--fsgd fsgd.txt--C 2gc0.mtx --surf
>> fsaverage lh --cortex --glmdir lh.glmdir//
>> > then mri_glmfit-sim to correct for multiple comparison.
>> > I want to study the subcortical regions and map it on MNI305.
>> How can
>> > I resume tha analysis for subcortical structures?
>> > Thank you for any help!
>> > Bests,
>> > John
>> >
>> >
>> > _______________________________________________
>> > Freesurfer mailing list
>> > Freesurfer@nmr.mgh.harvard.edu
>> > https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>
>> --
>> Douglas N. Greve, Ph.D.
>> MGH-NMR Center
>> gr...@nmr.mgh.harvard.edu
>> Phone Number: 617-724-2358
>> Fax: 617-726-7422
>>
>> Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
>> FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
>> www.nmr.mgh.harvard.edu/facility/filedrop/index.html
>> <http://www.nmr.mgh.harvard.edu/facility/filedrop/index.html>
>> Outgoing:
>> ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/
>>
>> _______________________________________________
>> Freesurfer mailing list
>> Freesurfer@nmr.mgh.harvard.edu
>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>
>>
>> The information in this e-mail is intended only for the person to
>> whom it is
>> addressed. If you believe this e-mail was sent to you in error and
>> the e-mail
>> contains patient information, please contact the Partners
>> Compliance HelpLine at
>> http://www.partners.org/complianceline . If the e-mail was sent to
>> you in error
>> but does not contain patient information, please contact the
>> sender and properly
>> dispose of the e-mail.
>>
>> _______________________________________________
>> Freesurfer mailing list
>> Freesurfer@nmr.mgh.harvard.edu
>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>>
>>
>> _______________________________________________ Freesurfer mailing
>> list Freesurfer@nmr.mgh.harvard.edu
>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The
>> information in this e-mail is intended only for the person to whom it
>> is addressed. If you believe this e-mail was sent to you in error and
>> the e-mail contains patient information, please contact the Partners
>> Compliance HelpLine at http://www.partners.org/complianceline . If
>> the e-mail was sent to you in error but does not contain patient
>> information, please contact the sender and properly dispose of the
>> e-mail.
>> _______________________________________________ Freesurfer mailing
>> list Freesurfer@nmr.mgh.harvard.edu
>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer The
>> information in this e-mail is intended only for the person to whom it
>> is addressed. If you believe this e-mail was sent to you in error and
>> the e-mail contains patient information, please contact the Partners
>> Compliance HelpLine at http://www.partners.org/complianceline . If
>> the e-mail was sent to you in error but does not contain patient
>> information, please contact the sender and properly dispose of the
>> e-mail.
>>
>>
>> _______________________________________________
>> Freesurfer mailing list
>> Freesurfer@nmr.mgh.harvard.edu
>> https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
>

--
Douglas N. Greve, Ph.D.
MGH-NMR Center
gr...@nmr.mgh.harvard.edu
Phone Number: 617-724-2358
Fax: 617-726-7422

Bugs: surfer.nmr.mgh.harvard.edu/fswiki/BugReporting
FileDrop: https://gate.nmr.mgh.harvard.edu/filedrop2
www.nmr.mgh.harvard.edu/facility/filedrop/index.html
Outgoing: ftp://surfer.nmr.mgh.harvard.edu/transfer/outgoing/flat/greve/

_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer
_______________________________________________
Freesurfer mailing list
Freesurfer@nmr.mgh.harvard.edu
https://mail.nmr.mgh.harvard.edu/mailman/listinfo/freesurfer


The information in this e-mail is intended only for the person to whom it is
addressed. If you believe this e-mail was sent to you in error and the e-mail
contains patient information, please contact the Partners Compliance HelpLine at
http://www.partners.org/complianceline . If the e-mail was sent to you in error
but does not contain patient information, please contact the sender and properly
dispose of the e-mail.

Reply via email to