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Hello all,


I have been running into a curious problem with a couple brains (8 out of 150 
seem to have this problem) running through the recon-all pipeline. Upon loading 
brainmask.mgz, T1.mgz, and corresponding white matter and pial surfaces in 
Freeview, my colleague and I received an error that T1.mgz failed to load. 
Segmentation and parcellation seemed to run smoothly and accurately, however, 
the size of the T1.mgz file was 0. Assuming the file had been corrupted somehow 
(our server through which we run recon-all and store our data has tons of 
available memory), we reran the brains affected. Upon loading up the same 
re-run surfaces, T1.mgz loaded into the GUI as white, washed out voxels, 
displaying no brain at all. The size of this file is large, as well as all 
other surface and volume files. Curiously, the brainmask file seems 
normalized/stripped fine and surfaces displayed over the T1 look accurately 
segmented. I attached a screenshot displaying the T1.mgz file and surfaces that 
I'm referring to.


I have a few concerns and questions. Because T1.mgz doesn't seem to be 
necessary for downstream manual editing and processing, can we proceed as 
normal, only displaying and using the brainmask file to make edits? Will our 
surface and volume metrics export properly without a usable T1 file? Lastly, 
any clues to how this might have occurred are welcomed. It seems like the 
mri_normalize step is the culprit, although the nu.mgz files corresponding to 
these brains seem normally sized.


Best,

Anneliis Sartin-Tarm

Associate Research Specialist
Neurocircuitry of Trauma and PTSD Study
UW-Madison Dept. Psychiatry
608-262-6375
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