Hi Brian,

Can you load a single volume in freeview to compare? Maybe also use similar 
window/level? The one in the picture appears smoothed to me (may due to 
trilinear sampling if it is not the first loaded volume).

Best,
Ruopeng


> On Apr 14, 2020, at 1:14 PM, Renner, Brian <brian.ren...@cshs.org> wrote:
> 
>         External Email - Use Caution        
> Hey Andrew;
> 
> Thanks for the response! To answer your questions, yes, We’re all 
> respectively on Macbook Pro retina displays. I hadn't compared the 
> visualization on a Windows machine, though I ostensibly could in the near 
> future. I have loaded up single vs. multiple volumes and noticed what you 
> say; would it be best to load the hypothetical highest resolution scan first? 
> ie. freeview -v highest.nii lower.nii. lowest.nii. --trilinear?
> 
> An example picture of this is shown below, with a standard 1mm^3 t2 flair 
> loaded in freeview with a higher resolution t2* as the first loaded scan, ie. 
> on the left freeview -v t2*file flair --trilinear vs. fsleyes t2*file flair 
> on the right:
> 
> <Screen Shot 2020-04-14 at 9.40.57 AM.png>
> Fig 1. This is the flair file compared side by side (fv --trilinear vs. 
> fsleyes, respectively).
> 
> <Screen Shot 2020-04-14 at 9.43.58 AM.png>
> Fig 2. This is the t2*file (0.65mm voxel width), which has both noticeable 
> quality drop and a different baseline intensity threshold at baseline between 
> freeview and fsleyes. 
> 
> <Screen Shot 2020-04-14 at 10.00.10 AM.png>
> Fig 3. This is the flair --trilinear vs. flair (noflags) vs. fsleyes flair, 
> respectively.
> 
>  Let me know what you think, and again thank you for the response!
> 
> BR
> 
> From: freesurfer-boun...@nmr.mgh.harvard.edu 
> <mailto:freesurfer-boun...@nmr.mgh.harvard.edu> 
> <freesurfer-boun...@nmr.mgh.harvard.edu 
> <mailto:freesurfer-boun...@nmr.mgh.harvard.edu>> on behalf of Hoopes, Andrew 
> <ahoo...@mgh.harvard.edu <mailto:ahoo...@mgh.harvard.edu>>
> Sent: Tuesday, April 14, 2020 9:25:08 AM
> To: Freesurfer support list <freesurfer@nmr.mgh.harvard.edu 
> <mailto:freesurfer@nmr.mgh.harvard.edu>>
> Subject: [External] Re: [Freesurfer] Freesurfer display resolution very low 
> compared to other viewers
>  
> Hi Brian,
>  
> A couple questions - are you visualizing on a mac retina screen? If so, there 
> will be a slight decrease from the standard resolution because the underlying 
> rendering library that we use unfortunately does not support retina 
> capabilities at this time. Also, are you loading single or multiple volumes? 
> Freeview uses the first volume loaded as the base image geometry, and all the 
> following volumes are resampled (if necessary) into this base geometry using 
> nearest neighbor interpolation. So if you’re working with 
> different-resolution images, it might help to enable linear interpolation as 
> the default resampling method by using the `--trilinear` freeview flag. If 
> that’s not the case, it’d be helpful to see a couple screenshots of the issue.
>  
> Hope that helps,
> Andrew
>  
> From: <freesurfer-boun...@nmr.mgh.harvard.edu 
> <mailto:freesurfer-boun...@nmr.mgh.harvard.edu>> on behalf of "Renner, Brian" 
> <brian.ren...@cshs.org <mailto:brian.ren...@cshs.org>>
> Reply-To: FS Help <freesurfer@nmr.mgh.harvard.edu 
> <mailto:freesurfer@nmr.mgh.harvard.edu>>
> Date: Monday, April 13, 2020 at 8:54 PM
> To: FS Help <freesurfer@nmr.mgh.harvard.edu 
> <mailto:freesurfer@nmr.mgh.harvard.edu>>
> Subject: [Freesurfer] Freesurfer display resolution very low compared to 
> other viewers
>  
>         External Email - Use Caution        
> Hello all! 
>  
> Inaugural message to the list; I will attempt to be brief with the project 
> description.
>  
> The setup is consistent between both versions 6.0.0 and 7.0.0-beta, run on a 
> high performance cluster, accessed through macOS terminal + Xquartz, most 
> recent versions all.
>  
> As it stands, our group is attempting to do subfield analysis of hippocampal 
> analysis and lesion measurement in MS subjects. We have noticed that there is 
> a major discrepancy of resolutions between files, which has irked some of our 
> physicians undertaking the lesion measurement. We need to resolve the lesions 
> down to 3mm and have noticed the quality between freeview and fsleyes of the 
> same nifti files will yield much lower display resolution. This is true for 
> most scans, though it has been compared using 1mm T2 FLAIR sequences as well 
> as T2* sequences with 0.65mm voxel space. I have been attempting to find a 
> workaround as the current solution for the physicians is to look at the files 
> in fsleyes and then measure them with the ruler tool in freeview. I can send 
> supporting pictures as necessary. 
>  
> Thank you in advance for any thoughts you may have!
>  
> BR
>  
> --
> Brian Renner, MD
> Research Associate, Neurology 
> brian.ren...@cshs.org <mailto:brian.ren...@cshs.org>
> 
> Cedars-Sinai
> 127 S. San Vicente Blvd, Suite A6600  :  Los Angeles CA 90048
> office 310-423-1589  :  mobile 310-658-3492  :  cedars-sinai.org 
> <https://www.cedars-sinai.org/> 
>  
> 
> 
> IMPORTANT WARNING: This message is intended for the use of the person or 
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> or the employee or agent responsible for delivering it to the intended 
> recipient, you are hereby notified that any dissemination, distribution or 
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> cooperation.
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