It is probably not going to work very well if you have some classes that only have one member. You can eliminate members of classes that only have a few members. If you really need to have those cases, there are hybrid ways to analyze the data (but you can't use an FSGD at that point)

On 2/6/2022 10:41 PM, Zeng, Victor (BIDMC - Keshavan - Psychiatry) wrote:

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Hi all,

I am doing an analysis and generating the FSGD. I understand sex and race are classes in this context, but something I was also hoping to regress out is the effects of scanner/sequences. We have a large participant size, so we have around 10+ scanner/sequences, which makes for a large amount of classes combinations, with some having just 1 (if not zero) fitting into a class.

Would you proceed with this nonetheless? If not, should scanner/sequence be something that we consider? Should we find some other way to adjust site (I don't think we can z-score...). Or can we consider site/scanner as a continuous variable

Victor Zeng
Beth Israel Deaconess Medical Center
Keshavan Lab
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