Let me summarize my last horrible send in a line:

"Traits are predictive of reproductive success, and reproductive success is the 
amplifier or attenuator of trait frequencies."

I don’t see any argument that the above sentence is tautological.  And I don’t 
hear anybody serious making any other claim than the above sentence.

My apologies to you all for thisAM….

Eric



> On Mar 30, 2026, at 6:53, Santafe <[email protected]> wrote:
> 
> I was on the point of trying to answer Nick a few days ago, while also 
> acknowledging that since I haven’t had time to read his paper, I should keep 
> it short.
> 
> It is helpful that EricC has posted in the meantime, because I often believe 
> I can understand what he means by something, whereas with Nick I often read 
> things that seem kinda familiar, but then I find some sentence that Nick 
> writes following a “therefore”, and I am baffled by what logic he thinks that 
> follows from, making me realize I probably didn’t understand what he 
> “actually meant” by the earlier sentences either.
> 
> But I will try a short in-line here, with EricC’s version, which is what I 
> was guessing Nick might have meant a few days ago when he said:
> 
>> This literature you cite often fails to make a distinction between evolution 
>> as a theory and the theory that explains evolution.  Evolution as a theory 
>> holds that organisms have descended through the ages they have become 
>> modified to the circumstances of their existence. It is a thesis about the 
>> causes of descent with modification.  Natural selection is a theory offered 
>> in explanation of that pattern of descent.  The literature you describe has 
>> often fused these two metaphors into one and therefore is fundamentally 
>> unfalsifiable as a theory that explains evolution. 
> 
> Here I was completely mystified what argument Nick understood himself to be 
> making.  Particularly referring to “the literature I cite”, since I sent him 
> George Price’s The Nature of Selection, which (in the actual print of the 
> article) says nothing of the kind. 
> 
> Put aside that I couldn’t track what the “two” were, or in what sense either 
> was a “metaphor”, other than that Nick labels them (and all other words; man 
> with a hammer) as such.
> 
> Anyway, moving on as promised:
> 
>> On Mar 30, 2026, at 0:41, Eric Charles <[email protected]> 
>> wrote:
>> 
>> I think this (EricS's reply) speaks to the "formalism" issue, and the value 
>> of the "flavor text". 
>> 
>> One of the big problems in evolutionary theory over the last century came 
>> from the desire for a very particular type of formalism, in which terms are 
>> all inter-defined, and as such, statements made within the system can't be 
>> "wrong" in an empirical sense. The classic example (so Nick and I assert in 
>> the incipient book) is the equation   where s stands for "selection" and W 
>> is "fitness". This has been in biology textbooks of a certain sort for well 
>> over half a century, and leads to Dawkins's "Selfish Gene" talk, among other 
>> things. It's hard to criticize on the surface, but, unfortunately, once you 
>> do that, you cannot usefully study the relationship between fitness and 
>> selection, because that-they-are-related becomes a truism! 
> 
> I _would_ have asked Nick: "What do you mean: is it that the sentence 
> `adaptedness is an outcome of natural selection' is a tautology, amounting to 
> nothing more than `fit are the fit'?”  I was guessing that might have been 
> Nick’s meaning, and it sounds like EricC’s meaning here.
> 
> I will take your word for the presence of bad writing and nonsense in 
> evolutionary textbooks a century ago (probably today, too; the ability of 
> many scientists to render coherent logic in ordinary English is often not 
> something to be proud of).  And I think I can remember somebody with a 
> biology degree (so journals are required to publish him), who writes 
> something like this (was it Pigliucci?  If not, I apologize to him for 
> bringing in his name.)
> 
> But if that is the complaint, it seems to me that that ship had sailed 
> already with Fisher, though he was so cryptic and imperious in his writing 
> and his personal style, that it had to wait 40 years for George Price to 
> explain to the rest of the community what Fisher was saying (and per Glen, 
> much more importantly, _doing_).  Steve Frank has written fairly well on 
> this; or at least, that is where I got it.  (I don’t know which of a 
> half-dozen papers might be the cleanest source to recommend here.)  In any 
> case, if people didn’t know it had sailed in 1930 or 1958, they certainly 
> should have known it had sailed by 1972 or 1990 (when Frank found Price’s 
> 1972 manuscript and published it).  de facto, most of the working literature 
> that has content already makes use of its having sailed, even if they don’t 
> remark on it, because they use Price Equations as accounting identifies 
> (among other organizing systems).  
> 
> If one is going to assert that there is nothing but tautology in what 
> population geneticists compute, and therefore they don’t ever predict 
> anything — a tautology can’t — then I would say that requires ignoring all 
> the main content of what one is reading in a very large number of papers.  
> There is an entire causal/predictive structure, and it can very much be wrong 
> in its imputations.  Often, the sources of being wrong can come from things 
> biologists don’t front as important elements of cause, where I argue they 
> should, so the things that are wrong can also be interesting.
> 
> What then am I claiming is the non-tautological content, which is there over 
> and over and over in tons of papers, which Fisher gestured at unhelpfully in 
> English, but partly did a very important thing with in math, which Steve 
> Frank acceptably describes, and which Price made didactic?
> 
> 1. First, obviously, we get rid of horoscope-style and Humpty-Dumpty-style 
> language.  We know that “fitness” can’t be doing much work in a causal 
> account if all it means is “I look at them, and they seem to be happy”, or if 
> it is meant to be a synonym for the even worse attributive: “design”.  
> (Remember the important part of the Vampire lore: they have to be invited 
> in!)  We have to actually say _what we mean a predictive theory to be 
> predicting_.   So the attempt to formalize fitness as “reproductive success, 
> absolute or relative, according to parent type”, is the declaration of the 
> observable to be the anchor for empiricism.  If you like, the “instrument” 
> that is to be employed. 
> 
> 1a.  Now, declaring an observable can’t in itself be “wrong” in Popper’s 
> sense, because it isn’t a logical conclusion.  What it can be, however, is 
> incoherent, and thus a gesture at a definition, which can’t ever be made into 
> an actual definition.  This is the important thing that Fisher did correctly 
> and explained horribly: making the point that “fitness” must be formalized as 
> a summary statistic (that’s a technical term, not a metaphor!) of your 
> high-dimensional observable.  The question of when you are _even saying 
> anything_ turns on when your summary statistic is coherently definable.  
> Wherever it is coherently defined, it _cannot_ be “falsifiable”, because now 
> we clearly have a definition that is a completely different kind of thing 
> than a putative derived conclusion.
> 
> 1b.  Next, since heredity plays out in diverse ways in different groups, 
> summary statistics defined for one won’t generally be defined for others.  
> Fisher, being a King, in many of the worst senses, and being out to capture 
> territory (negatively spun) and solve prediction problems (positively spun), 
> defined a variety of summary statistics from histories that are sequences of 
> population states connected through reproduction.  They aren’t all the same, 
> and they are not all capable of carrying the same “meanings”.   (I’ll get to 
> what that word means in a moment.)
> 
> 1c.  For objects that are suitably described as “replicators” (technical 
> term, not metaphor!), there is a fitness summary statistic that can also be 
> assigned as an attribute (just, a marking) of individual organisms.  For 
> organisms that reproduce sexually, or via a variety of complex lifecycles, 
> the summary statistics that Fisher defined to carry the label “fitness” 
> _cannot_ be assigned as attributes to any organism, because they are computed 
> from whole-population counts.  So quite apart from what you think you gain by 
> “marking” an individual organism with an attribute (the bacterial cells 
> carrying this allele have left 14.32 live daughters per starting cell in 6 
> generations in this laboratory instantiation of a population dynamic), for 
> these sexual-lifecycle summary statistics, you can’t even do that much.  
> 
> 1d,  Just btw (a thing nobody has any reason to care about), this is where it 
> is productive to go after Fisher, and the generations that don’t extend 
> beyond him in their methods.  His summary statistics are well-defined, so one 
> can’t deny that.  But they are not _all_ the summary statistics one might 
> try, and there are others (also well-defined) that can be constructed, which 
> do a better job of marking organisms and life-stages than Fisher’s fitnesses 
> do, and support all the same Price-like decompositions. That’s the kind of 
> thing I do.
> 
> 2. So at the end of all the “1” points above, we have an actual observable 
> that we have committed to, and that we intend some “theory” to explain or 
> predict in some way.  The whole content of a predictive theory is the 
> assertion that organisms have attributes in the here-and-now (variously 
> termed “traits”), which support prediction of the distributions of our 
> fitness summary statistics as time unfolds.  Again, those attributes aren’t 
> vague gestures like “seems to be doing well”; they should be things one can 
> commit to somehow: it is dark or light in color; it has softer or harder 
> shells or teeth or claws; etc. 
> 
> 2a. Geneticists try to capture the idea that traits in the here-and-now are 
> predictive of fitnesses as realized histories unfold, by defining sample 
> estimators for those dependencies in the form of regressions.  Again, if a 
> regression is defined, there can’t be anything “true” or “false” about it; it 
> is just a definition.  
> 
> 3. The Evolutionists, for some time, have built up terminology around all 
> this.  Samir Okasha’s book uses it (among other things) as a skeleton.  I 
> don’t enjoy the way they say it, but if one is trying to follow their 
> arguments, the terms are enough to do that.  The summary-statistic definition 
> of the observable is what they call “realized fitness”, and the regression 
> model on traits in the here-and-now is what they call the “propensity 
> interpretation”.  Yuck; but don’t shoot the messenger.  I probably wouldn’t 
> have coined those terms.
> 
> 3a.  It seems pretty inescapable to me that realized fitness and a regression 
> model on traits cannot be tautologically related, as one requires diachronic 
> observation even to assign, while the other is assignable (for any fixed 
> choice of regression coefficients) from a population state at a single time.  
> (It treats the population composition as a Markov state.)  
> 
> 3b.  Note that EricC’s s = 1-W above never entered any of what I said.  If a 
> selection coefficient is defined in some way as an algebraic function of 
> offspring numbers, that is just a layer of notation.  The existence of both 
> realized values W (convertible to realized values s), and model-predicted 
> expectations for W, derived from model-incorporated coefficients s, means 
> that the algebra isn’t meant to do other than convenience work _within_ 
> either layer, and the causal argument concerns the fitting of models to 
> sample data.  If textbook writers render this reality badly, then fine: go 
> after them.  But the flu designers who estimate what should go into an annual 
> vaccine don’t deserve to be tarred with that brush. 
> 
> 4. Finally we can get to the point of what they claim to be doing, and in 
> competent papers, are doing:  Are their regression models predictive, and are 
> they robust against things that the modeler didn’t notice, but that could 
> have been included?  Hashing out that question is the whole content of the 
> scientific literature and program.
> 
> 5. Where is conflation an actual hazard in the world I live in, what-exactly 
> is being conflated, and how might it get something wrong?  (So, we have 
> established falsifiable and in that sense meaningful; now I am talking about 
> false and thus interesting.)  Well, people might identify a trait that they 
> think confers a tendency to leave more offspring.  They might even be right 
> in their identification.  All that is on the “propensity” side.  The place 
> they can err is in supposing that, if they have identified a cause for a 
> tendency, then they can be assured of an outcome in the same direction (a 
> wrongful binding of the “propensity” term to the “realized” term), and the 
> only uncertainty will be the scale of the outcome effect.  This is an error I 
> think evolutionary biologists often do commit in their informal language, 
> even though the math in any paper wouldn’t let them get away with it, so they 
> don’t do it there.  Others, not even evolutionary biologists, but a kind of 
> groupie of the biologists from other domains in science, commit this error of 
> supposition and express it frequently in bar-quality conversation (I have a 
> certain conversation in a NASA working group in mind as I write this.)  The 
> slip between the cup of propensity, and the lip of realized outcomes, which 
> biologists don’t account for as fully as I think they should, is illustrated 
> nicely by magnetism:  The “tendency” for spins to align in solid-phase Iron 
> is identical at all temperatures.  However, when the iron is too hot, the 
> spins don’t macroscopically align “just a little”; rather, they don’t align 
> macroscopically at all.  Then, upon cooling just a little below the critical 
> temperature, they do macroscopically align, and the alignment rapidly becomes 
> “a lot” with separation of temperature below the critical value.  All this is 
> the lesson about counting that we learned from thermodynamics.  And while the 
> things being counted in evolution (completed lifecycles) are different from 
> the things counted in equilibrium thermo (pairs of aligned spins), the 
> counting argument applies equally well.
> 
> 
> Anyway…. Sorry for so many words.  I hope that I have given enough here to 
> explain why I am baffled when I hear modern people claim that “adaptation 
> occurs through natural selection” is “unfalsifiable”.  
> 
> The thing about where Dawkins goes wrong is another story, best told by not 
> quoting his own words, because he is such a rhetorician (even though his 
> earlier work suggests that he is capable of arguing properly).  But it 
> branches out of the points above, just on the point of mis-representing 
> summary statistics that cannot be object-attributes, as if they were object 
> attributes, and then, having set up that strawman, arguing that the only 
> recourse is to throw the whole thing out above the level of the gene, and 
> ignore that all the same problems continue to occur for genes, becoming quite 
> serious in the deeper past.  All that can totally be sorted out; there are no 
> fatal confusions, and metaphor isn’t tripping up anybody who wants to speak 
> and argue carefully.
> 
> Eric
> 
> 
> 
> 

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