Hello,

 

I have used the ensemble 3'UTR sequences (hg19) downloaded from UCSC, to do a
motif search exercise. Now I want to use the conservation scores for
alignments of 45 vertebrate genomes with Human (hg 19) on these motif
positions to see which of the motif sites are more significant in terms of
evolutionary conservation. Since I have used ENSEMBL sequences, can I still
use these conservation scores ie. will the positions of the UTR sequences
differ from the one used to derive the conservation scores?

 

Thanks

 

Manisha Brahmachary, Ph.D.

Associate Research Scientist

1130 St Nicholas Avenue

ICRC,Room 802,Columbia University

New York, NY 10032

 

 

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