I'm trying to validate PCR Primers.  Jim Kent had suggested it would be 
possible to do stepSize 1, so I figured I would try it out.

I tried running it on 1/2 the genome (chr 1 - 8), but after 90 minutes it still 
hadn't finished tiling the genome (it only took 8 minutes to do it at step size 
2), so I killed that process.

Greg

----- Original Message -----
From: "Galt Barber" <[email protected]>
To: "Gregory Dougherty" <[email protected]>
Cc: "genome" <[email protected]>
Sent: Wednesday, August 4, 2010 2:04:06 PM GMT -06:00 US/Canada Central
Subject: Re: [Genome] Segmentation Fault running gfServer

Even if it didn't segfault, you would not have enough memory to run 
stepSize 1, which is a very unusual option setting in any case.

Typical users are setting stepSize to 11 (the default tileSize)
or to 5 for a little extra sensitivity, at the cost of doubling the
RAM required.

What are you trying to align?

If you need very small alignments then the many wonderful
short-read-aligners like BWA do a good job.

-Galt

On 08/04/10 10:19, Gregory Dougherty wrote:
> On a server w/ 8 GB of RAM I tried running gfServer with a stepSize of 1, 
> tileSize of 11, on hg18.  

I got a Segmentation Fault.

Running it with stepSize of 2 works, and on a 4GB machine the stepSize 
of 2 generates a "not enough memory" error rather than a segfault.
> 
> Is this a known problem?  The machine is x86_64, running Linux.
> 
> TIA,
> 
> Greg
> _______________________________________________
> Genome maillist  -  [email protected]
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