Hi, Dear Support,

 

It would be easy to understand if they are at the end of a protein
sequence. However, could you please help me understand why there are so
many "X"es inside some sequences?

 

http://hgdownload.cse.ucsc.edu/goldenPath/hg19/multiz46way/alignments/re
fGene.exonAA.fa.gz

 

>NM_000152_gorGor1_18_19 51 0 0 Supercontig_0039638:17387-17539+

NXIXNELVXVTSEGAGLQLQKVTVLGVATAPQQVXSNGVPVSNFTYSPDTK

--

>NM_001079803_gorGor1_18_19 51 0 0 Supercontig_0039638:17387-17539+

NXIXNELVXVTSEGAGLQLQKVTVLGVATAPQQVXSNGVPVSNFTYSPDTK

--

>NM_001079804_gorGor1_18_19 51 0 0 Supercontig_0039638:17387-17539+

NXIXNELVXVTSEGAGLQLQKVTVLGVATAPQQVXSNGVPVSNFTYSPDTK

 

 

There are more than 30,000 sequences with X like that.   Please help.
Thanks!

 

Sean

 

Sean (Xiang) Li, Ph.D

Bioinformatics Scientist

Ambry Genetics

[email protected] <mailto:[email protected]> 

Direct 949-900-5504

Fax 949-900-5501

 

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