Hi Matteo,

While we don't yet have the SNP 134 data available on our main site, we 
do have the track currently in development. Since the track/data are 
available on our genome-preview site, you can download the data to use 
as input for your liftOver. Please note: Genome-preview 
(http://genome-preview.ucsc.edu/) allows users to preview tracks/data 
before they have been through our quality assurance process. Because 
genome-preview contains pre-release data, please use discretion when 
downloading and viewing data from genome-preview as it may still be 
undergoing changes and improvements.

Here is a link to the track controls/description of the preview of the 
All SNPs(134) track:
http://genome-preview.ucsc.edu/cgi-bin/hgTrackUi?db=hg19&g=snp134

Here is the preview of the data that you can use as your input to the 
liftOver:
http://hgdownload-test.cse.ucsc.edu/goldenPath/hg19/database/

Please contact the mail list ([email protected]) again if you have any 
further questions.

Katrina Learned
UCSC Genome Bioinformatics Group


On 9/30/11 10:15 AM, Katrina Learned wrote:
> Hi Matteo,
>
> First, I would suggest double-checking to make sure your bed file is
> correctly formatted. Here is detailed information about the bed format:
> http://genome.ucsc.edu/FAQ/FAQformat.html#format1. For example, make
> sure your chromosome fields are formatted as chr1 rather than chrom1.
>
> Second, if you are trying to lift specific regions of dbSNP134 data to
> hg18, then you might not be getting mappings because there are some
> regions of hg19 not in hg18. To see diffs between the two assemblies,
> you can use these tracks:
>
> on hg18
> Hg19 Diff: Contigs dropped or changed from NCBI build 36(hg18) to
> GRCh37(hg19)
> http://genome.ucsc.edu/cgi-bin/hgTrackUi?db=hg18&g=hg18ContigDiff
>
> on hg19
> Hg18 Diff: Contigs new to GRCh37/(hg19), not carried forward from NCBI
> build 36(hg18)
> http://genome.ucsc.edu/cgi-bin/hgTrackUi?db=hg19&g=hg19ContigDiff
>
> If you're still having trouble, please paste a sample section of your
> bed file in an email reply to the list so we can further troubleshoot
> the issue.
>
> Thanks!
>
> Katrina Learned
> UCSC Genome Bioinformatics Group
>
> On 9/30/11 2:12 AM, Matteo D'antonio wrote:
>> Hello,
>> I am finding problems in converting the coordinates of dbSNP134 from hg19 to
>> hg18. I have downloaded the coordinates from NCBI and I converted them into a
>> BED file. I use the original hg19ToHg18.over.chain.
>> liftOver snps.hg19.bed hg19ToHg18.over.chain snps.hg18.bed unMapped
>> The output file is always empty and all the coordinates have the tag 
>> "#Deleted
>> in new" in unMapped.
>> I have the same problem with a list of human genes in hg18 that I tried to 
>> map
>> to hg19.
>>
>> Can someone help?
>> Thanks!
>>
>> Matteo
>>
>> _______________________________________________
>> Genome maillist  -  [email protected]
>> https://lists.soe.ucsc.edu/mailman/listinfo/genome
> _______________________________________________
> Genome maillist  -  [email protected]
> https://lists.soe.ucsc.edu/mailman/listinfo/genome
_______________________________________________
Genome maillist  -  [email protected]
https://lists.soe.ucsc.edu/mailman/listinfo/genome

Reply via email to