Hi Pietrus, What you are seeing on the browser interface is the result of the compression of the wiggle file. Information can be found here:
http://genome.ucsc.edu/goldenPath/help/wiggle.html "For speed and efficiency, wiggle data is compressed and stored internally in 128 unique bins. This compression means that there is a minor loss of precision when data is exported from a wiggle track (*i.e.*, with output format "data points" or "bed format" within the table browser). The bedGraph<http://genome.ucsc.edu/goldenPath/help/bedgraph.html>format should be used if it is important to retain exact data when exporting." The files (chr*.phyloP44way.*.wigFix.gz ) that were downloaded are the actual data. Hope this answers your question. If you have further questions, please contact the mailing list: [email protected]. Vanessa Kirkup Swing UCSC Genome Bioinformatics Group ---------- Forwarded message ---------- From: 张朋 <[email protected]> Date: 2011/10/20 Subject: 答复: about the conservation To: Vanessa Kirkup Swing <[email protected]> Cc: "[email protected]" <[email protected]> Dear D Swing. The consevations I get from the Genome browser and table browser are same which can be seen in the pic 1 and pic2. But it differs from the conscore in the file "chr*.phyloP44way.*.wigFix.gz " seen in pic3. If the value in the pic2 means the conscore or not, and how can I get the conscore from website? *发件人:* Vanessa Kirkup Swing [[email protected]] *发送时间:* 2011年10月20日 2:28 *到:* 张朋 *Cc:* [email protected] *主题:* about the conservation Hi Pietrus, Can you tell us the 2 sources of data you are using to compare the conScores? Can you give us an example of a site that differs? If you could provide this information, it will help us determine the issue you are seeing. Please reply with this information to our mailing list: [email protected] so that our entire team can help you. Thanks! Vanessa Kirkup Swing UCSC Genome Bioinformatics Group Subject: Re: about the conservation Date: Wed, 19 Oct 2011 22:15:56 +0800 From: Pietrus.Z <[email protected]><[email protected]> To: genome <[email protected]> <[email protected]> Dear Editor: About two weeks from I wrote to you last time. So can you give me a reply about my question or who can I refer to about the question. Be waiting for your reply. 2011-10-19 Pietrus.Z 发件人: zhangpeng2 发送时间: 2011-10-08 16:42:45 收件人: genome-mirror; genome 抄送: 主题: about the conservation Dear Editor: I'm studying the conservation on the website:http://genome.ucsc.edu. But a problem come across me that theconScores of a same site are different as following. The data is from the file:http://database/hgdownload.cse.ucsc.edu/goldenPath/hg18/phyloP44way/primates/chr1.phyloP44way.primate.wigFix.gz Can you tell me why? looking forward to your reply, sincerely. 2011-10-08 zhangpeng2
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