Hi

 

I am trying to map Y chromosomal coordinates from build hg18 to hg19.
Last week when I used the Lift Genome Annotations Tool using the
NCBIBuild36 coordinates (chrY:12838588-13879980), I obtained the GRCh37
Coordinates (chrY:14328588-15370586) but now I get a message indicating
"Split in new".  

 

When I check in Ensembl it  gives the following message:

This data includes 10 gaps where the input coordinates could not be
mapped directly to the output assembly.

Y          Ensembl          .sdf      14726405        15370586
-           .           

Y          Ensembl          .sdf      14716432        14725776
-           .           

Y          Ensembl          .sdf      13226453        13226453
-           .           

Y          Ensembl          .sdf      14709281        14716431
-           .           

Y          Ensembl          .sdf      13219301        13219301
-           .           

Y          Ensembl          .sdf      14664254        14709280
-           .           

Y          Ensembl          .sdf      13174273        13174273
-           .           

Y          Ensembl          .sdf      14661473        14664253
-           .           

Y          Ensembl          .sdf      13171483        13171491
-           .

 

The region is a well behaved single copy X degenerate region that was
sequenced from, if I recall correctly, BAC clones from a single
individual. I was unable to find any reference to a recent change in the
Y annotation and was wondering if you could assist in trying to
ascertain what may have happened.  

 

With best wishes

Qasim
---
Qasim Ayub
Team 19: Human Evolution
Room Number E2-18
The Sulston Laboratories
The Wellcome Trust Sanger Institute
Wellcome Trust Genome Campus
Hinxton, Cambridge CB10 1SA
United Kingdom

E-mail: [email protected]
Tel:      +44-(0)-1223-834244 Ext:7652
Fax:     +44-(0)-1223-494919 

 




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