Actually J, the UCSC "numbering" system isn't about bases
or the gaps between bases at all, but rather intervals.
For example the first base in a chromosome is the interval [0-1)
The second base in a chromosome is the interval [1-2)
The first and second base is the interval [0-2)
And so forth.  We don't apply an actual number to any specific
base or gap between a base.  To reference a particular nucleotide
in a chromosome, the UCSC interval needs to be specified.
It depends upon what label number you want to apply to
that first base in the chromosome.  Is it base 0 or base 1 ?

Which came first ...

--Hiram


----- Original Message -----
From: "J Ireland" <[email protected]>
To: "Hiram Clawson" <[email protected]>
Cc: [email protected]
Sent: Thursday, March 22, 2012 4:27:00 PM
Subject: Re: [Genome] base vs gap numbering

Hey Hiram, 


Nice hearing from you! 


OK, I don't mean to be a pain but I think I'm still not getting my question 
across. Let me give it one more shot, and if I'm still not making sense maybe 
it's a discussion to have over beers at ISMB. 


>From everything I've read on the UCSC site, it seems that the UCSC convention 
>is to number the bases themselves. As you point out, however "the hash marks 
>are on the "gaps" between the bases" when you zoom in. I take this to mean 
>you're numbering the "gaps" - not the bases. So, what's not obvious to me is 
>why the numbered hash marks are not over the bases (at a zoomed in level of 
>course) if it's the bases that are being numbered. 


Thanks much, 
-J 
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