Hi,

I have a large wig file (about 16GB gzipped), it seems that
wigToBigWig takes too much memory. Of course, it is possible to
generated multiple bw files for each genome chunk (suppose that I
break the input file to multiple pieces). But it is inconvenient to
view many bw files and I don't fine a tool that can combine bw files
directly.

I'm wondering if there is a way to generate a single bigWig file for
such a large input. Would any export let me know? Thanks!

-- 
Regards,
Peng
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