> One possible cause could be pcre-config reporting -I/usr and causing 
> -I/usr/inc to be included before the SSL_INC path.

fwiw, here, at my shell/env

        pcre-config --libs --libs-posix --libs-cpp --cflags --cflags-posix
                -L/usr/local/lib64 -lpcre
                -L/usr/local/lib64 -lpcreposix -lpcre
                -L/usr/local/lib64 -lpcrecpp -lpcre
                -I/usr/local/include
                -I/usr/local/include

        pcre2-config --libs8 --libs-posix --cflags --cflags-posix
                -L/usr/local/lib64 -lpcre2-8
                -L/usr/local/lib64 -lpcre2-posix -lpcre2-8
                -I/usr/local/include
                -I/usr/local/include


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