[H] laptop 24/7

[Winterlight]

I am currently in temporary quarters for the next couple of months. 
With my WS I never turned anything off it would run untill I had to 
reboot for updates.  I have sent up a temporary office using a Lenovo 
Edge I7 Quad core, my good mechanical keyboard, mouse  and a 24 inch 
monitor. The laptop is plugged in and sitting on a Thermaltake giant 
fan laptop cooler. I turn it on in the morning and turn it off at 
night. I would like to just let it run all night as I want it to keep 
checking mail, and be ready to use when I turn the monitor back on in 
the morning rather then having to boot up, and set everything up 
again. Does it hurt a laptop to let it run like this 24/7? Thanks