Hi,

I am a novice at handling surfaces, and at using the Connectome 
Workbench/commandline, so apologies if the following is obvious.

We want to be able to perform connectivity analysis of subjects (both HCP and 
our own) using diffusion tractography. In order to directly compare the 
resultant (voxel-to-voxel) connectivity matrices across subjects, we would like 
to have a one-to-one correspondence between the tractography seed voxels in 
each subject. I presume that the best way to do this would be to first select 
the desired set of (inter-subject matched) seed points upon the aligned surface 
meshes already provided (BIG thanks!) by the HCP and then convert them to the 
(nearest) voxel? (I realise that this may be a surjective mapping). Are there 
functions/commands within the Connectome Workbench that can do this? Or are 
there more sensible approaches to achieving this?

Also, in [1], it states that the ‘standard grayordinate space’ (in CIFTI 
format) is used for achieving bijective inter-subject correspondence of the WM 
surface vertices and the subcortical voxels. However, I’m a bit confused how 
this bijective correspondence is maintained during the resampling from the 164K 
to the 32K meshes i.e. does the adaptive barycentric surface resampling method 
guarantee that the 32K-to-32K mappings are also bijective?

1. Glasser MF, Sotiropoulos SN, Wilson JA, Coalson TS, Fischl B, et al. (2013) 
The minimal preprocessing pipelines for the Human Connectome Project. 
NeuroImage 80: 105–124. doi:10.1016/j.neuroimage.2013.04.127.

Cheers,

M@
--
Matthew George Liptrot

<http://about.me/matthewliptrot>
Department of Computer Science
University of Copenhagen
&
Section for Cognitive Systems
Department of Applied Mathematics and Computer Science
Technical University of Denmark

http://about.me/matthewliptrot

<http://about.me/matthewliptrot>


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