Dear Prof. Smith,
Dear List,

one more question: would the Z-maps related to the second-last step step (dual regression to create volumetric representations if the IC) be available (they are not in the public release)?

This would greatly aid in interpreting/threshold the volumetric betas.

Thanks a lot in advance,

Nicola

On 07/06/2016 10:09 AM, Stephen Smith wrote:
Hi

Group-ICA is carried out in grayordinate space. Then:

For each subject, subject-wise grayordinate AND volumetric maps (versions of the group-ICA) are estimated using dual-regression, with node-timeseries normalisation, and outputs in units of GLM betas (parameter estimates) not Z.

These volumetric maps are then averaged across subjects to generate the group-average volumetric maps distributed from HCP.

So how you threshold these is up to you and depends what the intended usage for that is.......

Cheers.



On 6 Jul 2016, at 07:26, Nicola Toschi <tos...@med.uniroma2.it <mailto:tos...@med.uniroma2.it>> wrote:

Hi,

The volumetric version!

Thanks in advance,

Nicola


-------- Original message --------
From: Stephen Smith <st...@fmrib.ox.ac.uk <mailto:st...@fmrib.ox.ac.uk>>
Date: 04/07/2016 12:37 PM (GMT+01:00)
To: Nicola Toschi <tos...@med.uniroma2.it <mailto:tos...@med.uniroma2.it>> Cc: hcp-users <hcp-users@humanconnectome.org <mailto:hcp-users@humanconnectome.org>> Subject: Re: [HCP-Users] Exact Meaning of ICA maps in 800 subjects release

HI - do you mean the grayordinate or volumetric versions?
Cheers



On 4 Jul 2016, at 11:16, Nicola Toschi <tos...@med.uniroma2.it <mailto:tos...@med.uniroma2.it>> wrote:

Hi list,

This may be more of a MELODIC question, but I would be grateful for any input:

In the ICA release on 800+ subjects, what is the exact mathematical meaning / definition of the (non-binary) intensities of the different component volumes?

Are they easily relatable to a statistical map (I am looking to threshold them to study main clusters and possibly correct for multiple comparisons)?

Thanks in advance,

Nicola

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Stephen M. Smith, Professor of Biomedical Engineering
Head of Analysis,  Oxford University FMRIB Centre

FMRIB, JR Hospital, Headington, Oxford  OX3 9DU, UK
+44 (0) 1865 222726  (fax 222717)
st...@fmrib.ox.ac.uk <mailto:st...@fmrib.ox.ac.uk> http://www.fmrib.ox.ac.uk/~steve <http://www.fmrib.ox.ac.uk/%7Esteve>
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