Hi all

to chime in: we have done extensive work over the past year to replicate
and understand the prediction of IQ obtained in the Finn study. Our
manuscript is about to be submitted. Take away points:
-- the high effect size they find is partly due to small sample size (118
subjects) and to the specific subject sample
-- their method still has predictive value in the larger sample of
subjects, though the effect size is much reduced (similar to Megatrawl
without confounds)
-- the specifics of preprocessing/denoising and predictive model don't have
a huge effect on the final result (when enough subjects are included)

See also the work presented by Feilong Ma at OHBM this year, which took
great care in aligning subjects (MSMall + whole-brain hyperalignment) in a
much larger sample than the Finn study:
https://files.aievolution.com/hbm1701/abstracts/37710/3928_Ma.pdf

Happy to discuss further if someone is interested.
- Julien


*Postdoc | *Cedars-Sinai Medical Center // Caltech | +1 (310)423-8377 |
nigiri.caltech.edu/~jdubois

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